MedPath

Olaptesed Pegol

Generic Name
Olaptesed Pegol
Drug Type
Small Molecule
CAS Number
1390628-22-4
Unique Ingredient Identifier
MTM792B442
Background

Olaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation.

Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer

Phase 2
Not yet recruiting
Conditions
Metastatic Pancreatic Cancer
Interventions
First Posted Date
2021-05-25
Last Posted Date
2025-03-19
Lead Sponsor
TME Pharma AG
Target Recruit Count
60
Registration Number
NCT04901741

Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients

Phase 1
Active, not recruiting
Conditions
Glioblastoma
Interventions
First Posted Date
2019-10-10
Last Posted Date
2023-06-22
Lead Sponsor
TME Pharma AG
Target Recruit Count
27
Registration Number
NCT04121455
Locations
🇩🇪

Klinik und Poliklinik für Neurologie Schwerpunkt Klinische Neuroonkologie, Bonn, Germany

🇩🇪

Klinik für Strahlentherapie und Radioonkologie, Mannheim, Germany

🇩🇪

Klinik für Neurologie, Essen, Germany

and more 2 locations

NOX-A12 in Combination With Bortezomib and Dexamethasone in Relapsed Multiple Myeloma

Phase 2
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2012-01-30
Last Posted Date
2015-10-06
Lead Sponsor
TME Pharma AG
Target Recruit Count
28
Registration Number
NCT01521533
Locations
🇫🇷

Hôpital Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France

🇦🇹

Wilhelminenspital, Department of Medicine I, Center of Oncology and Hematology, Vienna, Austria

🇩🇪

University Hospital Freiburg, Medizinische Universitätsklinik, Innere Medizin I, Haematologie und Onkologie, Freiburg, Germany

and more 7 locations

NOX-A12 in Combination With Bendamustine and Rituximab in Relapsed Chronic Lymphocytic Leukemia (CLL)

Phase 2
Completed
Conditions
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2011-12-07
Last Posted Date
2017-05-22
Lead Sponsor
TME Pharma AG
Target Recruit Count
28
Registration Number
NCT01486797
Locations
🇦🇹

Medical University Innsbruck, Division of Hematology and Oncology, Innsbruck, Austria

🇧🇪

Institute Jules Bordet, Department of Hematology, Brussels, Belgium

🇧🇪

Cliniques universitaires Saint-Luc, Brussels, Belgium

and more 14 locations

NOX-A12 Multiple Ascending Dose Study in Healthy Volunteers

Phase 1
Completed
Conditions
Hematopoietic Stem Cell Transplantation
Interventions
Drug: NOX-A12 in combination with Filgrastim
First Posted Date
2010-09-03
Last Posted Date
2014-06-26
Lead Sponsor
TME Pharma AG
Target Recruit Count
12
Registration Number
NCT01194934
Locations
🇩🇪

Charité Research Organisation GmbH, Berlin, Germany

NOX-A12 First-in-human (FIH) Study

Phase 1
Completed
Conditions
Autologous Stem Cell Transplantation
Interventions
First Posted Date
2009-09-14
Last Posted Date
2014-06-26
Lead Sponsor
TME Pharma AG
Target Recruit Count
48
Registration Number
NCT00976378
Locations
🇩🇪

Scope Life Sciences GmbH, Hamburg, Germany

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