Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass that adheres t...
Human thrombin is indicated as an aid to hemostasis whenever oozing blood and minor bleeding from capillaries and small venules are accessible and control of bleeding by standard surgical techniques (such as suture, ligature, or cautery) is ineffective or impractical.
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International Research Partners, Doral, Florida, United States
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Elisenda Garsot Savall, Badalona, Barcelona, Spain
Duke University, Durham, North Carolina, United States
Stollery Alberta Children's hospital, Edmonton, Alberta, Canada
North Universitary Hospital, Amiens, France
Charles Nicolle Universitary Hospital, Rouen, France
Union Memorial Hospital, Baltimore, Maryland, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Northwest NeuroSpecialists, PPLC, Tucson, Arizona, United States
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