Donepezil
- Generic Name
- Donepezil
- Brand Names
- Adlarity, Aricept, Namzaric
- Drug Type
- Small Molecule
- Chemical Formula
- C24H29NO3
- CAS Number
- 120014-06-4
- Unique Ingredient Identifier
- 8SSC91326P
- Background
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some cases, is used to manage other ty...
- Indication
Donepezil, administered orally or via transdermal delivery system, is indicated for the treatment of dementia of the Alzheimer's type. It is also available as an extended-release capsule in combination with memantine for the treatment of moderate-to-severe dementia of the Alzheimer's type in patients previously stabilized on 10mg of donepezil hydrochloride o...
- Associated Conditions
- Alzheimer's Disease (AD), Dementia With Lewy Body Disease, Dementia due to Parkinson's disease, Dementia of the Alzheimer's Type, Vascular Dementia (VaD), Moderate Alzheimer's Type Dementia, Severe Alzheimer's Type Dementia
- Associated Therapies
- -
Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease
- Conditions
- First Posted Date
- 2000-08-21
- Last Posted Date
- 2009-01-15
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 45
- Registration Number
- NCT00006399
- Locations
- 🇺🇸
Clinical Neuroscience Research Unit, University of Vermont, Burlington, Vermont, United States
Study of the Pathogenesis of Rett Syndrome
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2005-06-24
- Target Recruit Count
- 120
- Registration Number
- NCT00004807
Memory Impairment Study (Mild Cognitive Impairment Study)
- Conditions
- First Posted Date
- 1999-11-01
- Last Posted Date
- 2009-12-11
- Lead Sponsor
- National Institute on Aging (NIA)
- Registration Number
- NCT00000173
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸University of California, Los Angeles, Los Angeles, California, United States
🇺🇸Baumel-Eisner Neuromedical Institute, Boca Raton, Boca Raton, Florida, United States
Drug Development Updates
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