Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation

Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.

First Posted Date
2014-04-08
Last Posted Date
2018-06-12
Lead Sponsor
Tao Zhang
Target Recruit Count
68
Registration Number
NCT02107170
Locations
🇨🇳

First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China

Effect of Deksmedetomidine and Remifentanil in Extubation Agitation

First Posted Date
2014-04-04
Last Posted Date
2014-04-04
Lead Sponsor
Diskapi Yildirim Beyazit Education and Research Hospital
Target Recruit Count
90
Registration Number
NCT02104297
Locations
🇹🇷

Reyhan Polat, Ankara, Turkey

Conditions of Diagnostic Panendoscopy of the Upper Airway Under Propofol Remifentanil General Anesthesia

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-03-20
Last Posted Date
2014-03-20
Lead Sponsor
Centre Hospitalier Universitaire de Besancon
Target Recruit Count
256
Registration Number
NCT02093143
Locations
🇫🇷

Centre Hospitalier Régional Universitaire, Besançon, France

🇫🇷

CHRU Besançon, Besançon, France

The Effect of Analgesia Based Sedation Protocol on Brain Function of Critical Care Patients

First Posted Date
2014-03-05
Last Posted Date
2014-07-16
Lead Sponsor
Peking University People's Hospital
Target Recruit Count
100
Registration Number
NCT02078583

Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.

First Posted Date
2014-02-04
Last Posted Date
2015-08-13
Lead Sponsor
Aarhus University Hospital
Target Recruit Count
60
Registration Number
NCT02053818
Locations
🇩🇰

Aarhus University Hospital, Aarhus N, Denmark

Remifentanil for Sedation of Patients With Traumatic Brain Injury (TBI)

Completed
Conditions
Interventions
First Posted Date
2014-01-30
Last Posted Date
2017-02-01
Lead Sponsor
Joseph D. Tobias
Target Recruit Count
38
Registration Number
NCT02049320
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients

First Posted Date
2014-01-23
Last Posted Date
2016-01-08
Lead Sponsor
Tianjin Medical University General Hospital
Target Recruit Count
180
Registration Number
NCT02043366
Locations
🇨🇳

Tianjin Medical University General Hospital, Tianjin, Tianjin, China

Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain

First Posted Date
2014-01-09
Last Posted Date
2016-10-18
Lead Sponsor
St. Antonius Hospital
Target Recruit Count
126
Registration Number
NCT02031016
Locations
🇳🇱

St. Antonius Hospital, Nieuwegein, Netherlands

Remifentanil for General Anesthesia in the Context of Immaturity

First Posted Date
2014-01-08
Last Posted Date
2017-08-30
Lead Sponsor
University Hospital, Rouen
Target Recruit Count
53
Registration Number
NCT02029898
Locations
🇫🇷

CHU de Rouen, Rouen, France

Effect-site Concentration of Remifentanil for Blunting Hemodynamic Responses to Double-lumen Endobronchial Intubation

Not Applicable
Conditions
Interventions
First Posted Date
2013-12-04
Last Posted Date
2013-12-04
Lead Sponsor
Jeju National University School of Medicine
Target Recruit Count
50
Registration Number
NCT02001285
Locations
🇰🇷

Jeju National University Hospital, Jeju-si, Jeju Special Self-Governing Province, Korea, Republic of

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