Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

the Effective Bolus Dose of Remifentanil for Laryngeal Mask Airway (LMA) Insertion in Children

Not Applicable
Completed
Conditions
Respiratory Complication
Interventions
Drug: Remifentanil
First Posted Date
2013-08-08
Last Posted Date
2015-07-16
Lead Sponsor
Sangjin Park
Target Recruit Count
50
Registration Number
NCT01919203
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine, Yeungnam University hospital, Nam gu, Daegu, Korea, Republic of

Optimal Effect-site Concentration of Remifentanil for Inhibiting Response to Laryngeal Mask Airway (LMA) Removal

Not Applicable
Completed
Conditions
Respiratory Complication
Interventions
Drug: Remifentanil
First Posted Date
2013-08-02
Last Posted Date
2014-08-25
Lead Sponsor
Sangjin Park
Target Recruit Count
128
Registration Number
NCT01915108

The Medasense Study

Not Applicable
Completed
Conditions
Pain
Interventions
Drug: Propofol
Drug: Remifentanil
First Posted Date
2013-07-30
Last Posted Date
2015-04-06
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
96
Registration Number
NCT01912118
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

Remifentanil Intravenous Patient Controlled Analgesia (IVPCA) for Ablation of Idiopathic Ventricular Tachycardia

Phase 4
Completed
Conditions
Tachycardia, Ventricular
Interventions
Drug: Remifentanil
First Posted Date
2013-07-17
Last Posted Date
2018-01-02
Lead Sponsor
NYU Langone Health
Target Recruit Count
16
Registration Number
NCT01901575
Locations
🇺🇸

NYU Langone Medical Center, New York, New York, United States

Esmolol Pretreatment on Pain During Injection of Propofol

Not Applicable
Completed
Conditions
Pain
Interventions
Drug: Normal saline
Drug: Esmolol
Drug: Remifentanil
Drug: propofol
First Posted Date
2013-06-25
Last Posted Date
2016-02-08
Lead Sponsor
Kyungpook National University Hospital
Target Recruit Count
120
Registration Number
NCT01885364
Locations
🇰🇷

Kyungpook National University Hospital, Daegu, Korea, Republic of

The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation in Normotensive and Hypertensive Patients

Not Applicable
Completed
Conditions
Intubation, Intratracheal
Interventions
Drug: Remifentanil
First Posted Date
2013-06-19
Last Posted Date
2015-04-09
Lead Sponsor
Severance Hospital
Target Recruit Count
44
Registration Number
NCT01880931
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of

Atropine Effects in Anaesthesia With Sufentanil vs. Remifentanil

First Posted Date
2013-06-07
Last Posted Date
2014-01-31
Lead Sponsor
University Medical Center Groningen
Target Recruit Count
70
Registration Number
NCT01871935
Locations
🇳🇱

University Medical Center Groningen, Groningen, Netherlands

Sedation Versus General Anesthesia for Endovascular Therapy in Acute Stroke - Impact on Neurological Outcome

Not Applicable
Completed
Conditions
Ischemic Stroke
Interventions
Drug: Sevorane Remifentanil
Drug: Remifentanil
First Posted Date
2013-06-07
Last Posted Date
2017-10-11
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Target Recruit Count
90
Registration Number
NCT01872884
Locations
🇸🇪

Sahlgrenska University Hospital, Gothenburg, Sweden

Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy

First Posted Date
2013-04-17
Last Posted Date
2013-11-13
Lead Sponsor
Bezmialem Vakif University
Target Recruit Count
80
Registration Number
NCT01833819
Locations
🇹🇷

Bezmialem Vakif University Faculty of Medicine, Istanbul, Turkey

Comparison of Intravenous Anesthetics to Volatile Anesthetics on Postoperative Cognitive Dysfunction

First Posted Date
2013-03-12
Last Posted Date
2023-06-22
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
684
Registration Number
NCT01809041
Locations
🇨🇳

Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong, China

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