Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

Median Effective Dose of Remifentanil for the Prevention of Pain Caused by the Injection of Rocuronium

Not Applicable
Conditions
Rocuronium
Injection Pain
Interventions
Drug: Remifentanil
First Posted Date
2022-02-01
Last Posted Date
2022-02-01
Lead Sponsor
Yangzhou University
Target Recruit Count
70
Registration Number
NCT05217238
Locations
🇨🇳

the Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China

The Comparison of Remimazolam With Propofol in Core Body Temperature

Phase 4
Completed
Conditions
Hypothermia; Anesthesia
Interventions
Drug: Remifentanil
First Posted Date
2022-01-31
Last Posted Date
2022-02-14
Lead Sponsor
Wonkwang University Hospital
Target Recruit Count
90
Registration Number
NCT05215834
Locations
🇰🇷

Wonkwag UH, Iksan, Korea, Republic of

ANI and Remifentanil in Skull Pin Fixation.

Phase 4
Completed
Conditions
Pain, Procedural
Interventions
Drug: Remifentanil
First Posted Date
2021-11-18
Last Posted Date
2024-03-21
Lead Sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Target Recruit Count
27
Registration Number
NCT05125328
Locations
🇨🇳

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan

Compare the Effects of Remifentanil and Fentanyl on the Duration of Mechanical Ventilation of ICU Patients

First Posted Date
2021-08-20
Last Posted Date
2021-08-20
Lead Sponsor
Capital Medical University
Target Recruit Count
254
Registration Number
NCT05014711
Locations
🇨🇳

ICU, Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass

First Posted Date
2021-08-13
Last Posted Date
2023-11-30
Lead Sponsor
matthieu clanet
Target Recruit Count
183
Registration Number
NCT05004519
Locations
🇧🇪

CHIREC Delta Hospital, Brussels, Belgium

Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in ICU

Phase 3
Conditions
Analgesia
Interventions
Drug: Remifentanil
Drug: Fentanyl
First Posted Date
2021-08-12
Last Posted Date
2022-08-11
Lead Sponsor
Southeast University, China
Target Recruit Count
138
Registration Number
NCT05003570
Locations
🇨🇳

Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

🇨🇳

The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China

🇨🇳

Anhui Provincial Hospital, Hefei, Anhui, China

and more 14 locations

Opioid-Free Anesthesia in Cardiac Surgery

First Posted Date
2021-06-25
Last Posted Date
2024-02-28
Lead Sponsor
University Hospital, Rouen
Target Recruit Count
268
Registration Number
NCT04940689
Locations
🇫🇷

Amiens Univesrity Hospital, Amiens, France

🇫🇷

Rouen University Hospital, Rouen, France, Normandy, France

🇫🇷

Lille Hopistal University, Lille, France

and more 2 locations

Evaluation of Remifentanil and Dexmedetomidine in Patients With Noninvasive Mechanical Ventilation Intolerance

Not Applicable
Conditions
NIV Intolerance
Interventions
Drug: Remifentanil
Drug: Dexmedetomidine
First Posted Date
2021-02-02
Last Posted Date
2021-03-16
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
178
Registration Number
NCT04734418
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil

Phase 1
Completed
Conditions
Anesthesia
Interventions
Drug: Remimazolam
Drug: Remifentanil
First Posted Date
2020-12-17
Last Posted Date
2023-09-11
Lead Sponsor
Paion UK Ltd.
Target Recruit Count
28
Registration Number
NCT04670471
Locations
🇳🇱

University Medical Center Groningen, Groningen, Netherlands

The Effect of Dexmedetomidine During Opioid Free Anesthesia on Postoperative Recovery After Gastrectomy

Not Applicable
Completed
Conditions
Gastric Cancer
Interventions
Drug: Dexmedetomidine
Drug: Remifentanil
First Posted Date
2020-08-27
Last Posted Date
2022-06-23
Lead Sponsor
Gangnam Severance Hospital
Target Recruit Count
68
Registration Number
NCT04529135
Locations
🇰🇷

Gangnam Severance Hospital, Seoul, Korea, Republic of

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