Tolterodine

Generic Name
Tolterodine
Brand Names
Detrol, Detrusitol
Drug Type
Small Molecule
Chemical Formula
C22H31NO
CAS Number
124937-51-5
Unique Ingredient Identifier
WHE7A56U7K
Background

Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Associated Conditions
Urinary Urge Incontinence
Associated Therapies
-

SSR240600C Treatment in Women With Overactive Bladder

First Posted Date
2007-11-27
Last Posted Date
2016-05-26
Lead Sponsor
Sanofi
Target Recruit Count
345
Registration Number
NCT00564226
Locations
🇺🇸

Sanofi-Aventis Aministrative Office, Bridgewater, New Jersey, United States

🇵🇹

Sanofi-Aventis Administrative Office, Porto Salvo, Portugal

Pharmacological vs Surgical Treatment for Mixed Incontinence

First Posted Date
2007-08-30
Last Posted Date
2024-07-29
Lead Sponsor
Imperial College London
Registration Number
NCT00523068
Locations
🇬🇧

Demetri C Panayi, London, United Kingdom

Evaluation of the Link Between Bladder Sensation and Changes in Skin Electrical Conductance and Heart Rate.

First Posted Date
2007-06-04
Last Posted Date
2021-01-27
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
28
Registration Number
NCT00481728
Locations
🇨🇭

Pfizer Investigational Site, Zurich, Switzerland

Overactive Bladder Innovative Therapy Trial (OrBIT)

First Posted Date
2007-03-16
Last Posted Date
2013-05-16
Lead Sponsor
Uroplasty, Inc
Target Recruit Count
100
Registration Number
NCT00448175
Locations
🇺🇸

Uroplasty, Inc, Minnetonka, Minnesota, United States

Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)

First Posted Date
2007-03-08
Last Posted Date
2015-03-24
Lead Sponsor
Pfizer
Target Recruit Count
1712
Registration Number
NCT00444925
Locations
🇺🇦

Pfizer Investigational Site, Zaporizhzhia, Ukraine

ELB245 for 12 Weeks Versus 4mg Tolterodine in Patients With Incontinent Overactive Bladder (OAB)

Phase 2
Terminated
Conditions
First Posted Date
2007-02-23
Last Posted Date
2007-08-08
Lead Sponsor
elbion AG
Target Recruit Count
275
Registration Number
NCT00439192
Locations
🇸🇪

Danderyds Hospital, Stockholm, Sweden

🇸🇪

University Hospital Uppsala, Uppsala, Sweden

🇸🇪

Karolinska University Hospital Huddinge, Stockholm, Sweden

and more 12 locations

Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects

Phase 4
Completed
Conditions
Interventions
First Posted Date
2006-12-20
Last Posted Date
2008-01-15
Lead Sponsor
Novartis
Target Recruit Count
162
Registration Number
NCT00413790
Locations
🇺🇸

Investigative Site, Dallas, Texas, United States

A Double-Blind, Paralleled Study Comparing Efficacy/Safety of Solifenacin to Tolterodine in Overactive Bladder Patients

First Posted Date
2006-08-25
Last Posted Date
2008-04-10
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
246
Registration Number
NCT00368706

Effects of Tolterodine, a Non-Specific Muscarinic Antagonist, on Gastrointestinal Transit in Healthy Subjects

Phase 2
Completed
Conditions
First Posted Date
2006-06-01
Last Posted Date
2011-03-23
Lead Sponsor
Mayo Clinic
Target Recruit Count
36
Registration Number
NCT00332137
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

A Comparison of Tolterodine and Placebo Treatments on Nocturnal Frequency and Sleep Quality in Women After Menopause.

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2006-05-09
Last Posted Date
2018-03-29
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
19
Registration Number
NCT00323635
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Brigham & Women's Hospital, Boston, Massachusetts, United States

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