MedPath

Adebrelimab

Generic Name
Adebrelimab
Drug Type
Biotech
CAS Number
2247114-85-6
Unique Ingredient Identifier
1XBY50W1OX
Background

Adebrelimab is under investigation in clinical trial NCT03711305 (Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-stage (ES) Small Cell Lung Cancer (SCLC)).

Indication

用于与卡铂和依托泊苷联合用于广泛期小细胞肺癌患者的一线治疗。

Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial

Phase 2
Recruiting
Conditions
Small Cell Lung Cancer (SCLC)
Interventions
First Posted Date
2024-07-03
Last Posted Date
2024-07-03
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
104
Registration Number
NCT06485544
Locations
🇨🇳

Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an, Shannxi, China

A Study of Adebrelimab Combined With Apatinib Mesylate and Chemotherapy for Neoadjuvant Therapy and Biomarker Analysis in Limited-stage Small Cell Lung Cancer

Phase 2
Recruiting
Conditions
Small Cell Lung Cancer Limited Stage
Interventions
First Posted Date
2024-07-03
Last Posted Date
2025-04-15
Lead Sponsor
Jin Ying
Target Recruit Count
38
Registration Number
NCT06483282
Locations
🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

Perioperative Treatment of Resectable Adenocarcinoma of Esophagogastric Junction by Immunotherapy (Adebrelimab) Combined With Chemotherapy (XELOX): a Prospective, Single-center, Feasibility Study

Phase 2
Recruiting
Conditions
Esophagogastric Junction Adenocarcinoma
Interventions
First Posted Date
2024-07-01
Last Posted Date
2024-07-01
Lead Sponsor
Ruijin Hospital
Target Recruit Count
26
Registration Number
NCT06482788
Locations
🇨🇳

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

Adebrelimab Plus Apatinib for Maintenance Therapy of Extensive Stage Small Cell Lung Cancer

First Posted Date
2024-06-28
Last Posted Date
2025-01-06
Lead Sponsor
Yunpeng Liu
Target Recruit Count
38
Registration Number
NCT06480864
Locations
🇨🇳

The First Hospital of China Medical University, Shenyang, China

A Study of Adebrelimab Combined With Chemoradiotherapy in the Treatment of Esophageal Small Cell Carcinoma

Phase 2
Not yet recruiting
Conditions
Esophageal Small Cell Carcinoma
Interventions
First Posted Date
2024-06-27
Last Posted Date
2024-06-27
Lead Sponsor
Zhangzhou Municipal Hospital
Target Recruit Count
40
Registration Number
NCT06478264

Adebrelimab in Combination With NALIRIFOX in Locally Advanced Pancreatic Cancer

First Posted Date
2024-06-26
Last Posted Date
2024-08-09
Lead Sponsor
Fudan University
Target Recruit Count
87
Registration Number
NCT06475326
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, China

Adebrelimab + Apatinib in SCLC Maintenance Therapy

Phase 2
Recruiting
Conditions
SCLC
Interventions
First Posted Date
2024-06-26
Last Posted Date
2024-06-26
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
60
Registration Number
NCT06475209
Locations
🇨🇳

Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an, Shannxi, China

Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer

Phase 2
Recruiting
Conditions
Gastric Cancer
Interventions
First Posted Date
2024-06-26
Last Posted Date
2024-06-26
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
42
Registration Number
NCT06475417
Locations
🇨🇳

Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an, Shannxi, China

Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer

Phase 2
Not yet recruiting
Conditions
Advanced Breast Cancer
Hormone-receptor-positive Breast Cancer
Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
Interventions
First Posted Date
2024-06-24
Last Posted Date
2024-12-20
Lead Sponsor
Fudan University
Target Recruit Count
32
Registration Number
NCT06470672
Locations
🇨🇳

Fudan Cancer Hospital, Shanghai, Shanghai, China

To Evaluate the Efficacy of Adebrelimab Combined With Chemotherapy After HIFU Induction Neoadjuvant Therapy HR+/HER2- Breast Cancer

Phase 2
Not yet recruiting
Conditions
HR+/HER2- Breast Cancer
Breast Cancer
Interventions
Procedure: High Intensity Focused Ultrasoun(HIFU)
First Posted Date
2024-06-24
Last Posted Date
2024-06-24
Lead Sponsor
The First Affiliated Hospital with Nanjing Medical University
Target Recruit Count
29
Registration Number
NCT06470633
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