Sodium lauryl sulfate

Overview

Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.

Indication

SLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design	2024/04/17	NCT06369675	Phase 1	Completed	Moberg Pharma AB
Dermal Tolerability of Dapsone Gel in Healthy Volunteers	2014/04/21	NCT02117752	Phase 1	Completed	Almirall, S.A.
Dermal Safety Study to Evaluate Potential Irritation of Abametapir Lotion	2014/02/13	NCT02061813	Phase 1	Completed	Dr. Reddy's Laboratories Limited
Patch Test of Benzalkonium Chloride Disinfectant Spray	2013/01/08	NCT01762982	Not Applicable	Completed	GlaxoSmithKline
21 Day Irritancy Test of Azelaic Acid Pre-foam Formulation	2011/09/08	NCT01430312	Phase 1	Completed	LEO Pharma
Cumulative Skin Irritation Potential of a New 25 mg Nicotine Patch	2009/08/27	NCT00967174	Phase 1	Completed	McNeil AB

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
Esomeprazole Magnesium	Mylan Pharmaceuticals Inc.	0378-2350	ORAL	N/A	11/15/2023
Esomeprazole Magnesium	Mylan Pharmaceuticals Inc.	0378-2351	ORAL	N/A	11/15/2023
TRIMO SAN	CooperSurgical, Inc.	59365-5030	VAGINAL	0.1 mg in 1 g	6/16/2022
Trimo-San	Denison Pharmaceuticals, LLC	0295-5030	VAGINAL	0.1 mg in 1 g	9/11/2019

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
PLAX ANTI-PLAQUE DENTAL RINSE	johnson & johnson inc	01942506	Liquid - Dental	0.25 %	12/31/1988

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

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