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Ofloxacin

Generic Name
Ofloxacin
Brand Names
Ocuflox
Drug Type
Small Molecule
Chemical Formula
C18H20FN3O4
CAS Number
82419-36-1
Unique Ingredient Identifier
A4P49JAZ9H

Overview

A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Background

A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Indication

For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.

Associated Conditions

  • Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
  • Acute Otitis Media (AOM)
  • Bacterial Infections
  • Cervicitis
  • Community Acquired Pneumonia (CAP)
  • Complicated Urinary Tract Infection
  • Conjunctivitis
  • Epididymitis
  • Hansen's Disease
  • Nongonococcal urethritis
  • Otitis Externa
  • Prostatitis
  • Skin and Subcutaneous Tissue Bacterial Infections
  • Spontaneous Bacterial Peritonitis (SBP)
  • Traveler's Diarrhea
  • Ulcerative keratitis
  • Acute Pelvic inflammatory disease
  • Acute, uncomplicated Gonorrhea
  • Chronic suppurative Otitis media
  • Uncomplicated Cystitis

Clinical Trials

Diagnostics of Chronic Endometritis in Infertility
Not Applicable
Completed
Posted: 2023/07/14
Sponsor:
Jagiellonian Univers...
ID:NCT05946655
Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Bacterial Conjunctivitis
Phase 2
Completed
Posted: 2023/04/18
Sponsor:IVIEW Therapeutics I...
ID:NCT05816070
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome
Phase 1
Recruiting
Posted: 2022/03/31
Sponsor:
Central Hospital, Na...
ID:NCT05302531
Ofloxacin Concentration-toxicity Relationship in the Elderly
Not Applicable
Recruiting
Posted: 2020/08/03
Sponsor:Centre Hospitalier U...
ID:NCT04496024
Nasal Ointment on Epistaxis of Nasotracheal Intubation in Children
Not Applicable
Completed
Posted: 2020/06/11
Sponsor:
Ajou University Scho...
ID:NCT04426409

FDA Approved Products

Ofloxacin
Manufacturer:Aidarex Pharmaceuticals LLC
Route:AURICULAR (OTIC)
Strength:3 mg in 1 mL
Approved: 2014/01/20
NDC:33261-737
Ofloxacin
Manufacturer:REMEDYREPACK INC.
Route:OPHTHALMIC
Strength:3 mg in 1 mL
Approved: 2024/01/04
NDC:70518-0192
ofloxacin
Manufacturer:A-S Medication Solutions
Route:OPHTHALMIC
Strength:3 mg in 1 mL
Approved: 2023/08/31
NDC:50090-6795
Ofloxacin
Manufacturer:Amneal Pharmaceuticals NY LLC
Route:AURICULAR (OTIC)
Strength:3 mg in 1 mL
Approved: 2023/05/11
NDC:69238-1616
Ofloxacin
Manufacturer:RPK Pharmaceuticals, Inc.
Route:OPHTHALMIC
Strength:3 mg in 1 mL
Approved: 2023/04/24
NDC:53002-3324

Singapore Approved Products

OFCIN FILM COATED TABLET 400 mg
Manufacturer:Y.S.P. INDUSTRIES (M) SDN BHD
Form:TABLET, FILM COATED
Strength:400 mg
Online:Yes
Approved: 1998/09/25
Approval:SIN10118P
FLOVID 200
Manufacturer:HOVID Bhd.
Form:TABLET, FILM COATED
Strength:200.00 MG
Online:Yes
Approved: 2006/09/28
Approval:SIN13219P
OFCIN FILM COATED TABLET 200 mg
Manufacturer:YUNG SHIN PHARMACEUTICAL IND CO LTD, YSP Industries (M) Sdn Bhd
Form:TABLET, FILM COATED
Strength:200 mg
Online:Yes
Approved: 1998/09/25
Approval:SIN10119P
OFLOX TABLET 200 mg
Manufacturer:BROWN & BURK PHARMACEUTICAL LTD
Form:TABLET, FILM COATED
Strength:200 mg
Online:Yes
Approved: 2000/12/13
Approval:SIN11433P
AKILEN TABLET 200 mg
Manufacturer:PT SANBE FARMA
Form:TABLET, FILM COATED
Strength:200 mg
Online:Yes
Approved: 2000/08/24
Approval:SIN11377P

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