Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
Trial of the Use of Doxycycline After Rotator Cuff Repair
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2016-05-09
- Lead Sponsor
- Milton S. Hershey Medical Center
- Registration Number
- NCT02388477
- Locations
- 🇺🇸
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States
Effects of Long Term Antibiotic Therapy on Exacerbation Rate in Stable COPD Patients
- Conditions
- Interventions
- First Posted Date
- 2014-12-03
- Last Posted Date
- 2017-07-26
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 222
- Registration Number
- NCT02305940
- Locations
- 🇬🇧
Aintree University Hospital NHS Foundation Trust, Liverpool, United Kingdom
🇬🇧Royal Brompton and Harefield Hospital NHS Foundation Trust, London, United Kingdom
🇬🇧St Georges University Hospitals NHS Foundation Trust, London, United Kingdom
Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana
- Conditions
- Interventions
- First Posted Date
- 2014-11-02
- Last Posted Date
- 2017-03-23
- Target Recruit Count
- 200
- Registration Number
- NCT02281643
- Locations
- 🇬🇭
Agogo Presbyterian Hospital, Agogo, Asante Akim North District, Ghana
Doxycycline to Upgrade Organ Response in Light Chain (AL) Amyloidosis Trial
- First Posted Date
- 2014-08-04
- Last Posted Date
- 2021-07-09
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 32
- Registration Number
- NCT02207556
- Locations
- 🇺🇸
Froedtert & Medical College of Wisconsin, Milwaukee, Wisconsin, United States
RosaC-RF : Bipolar Radiofrequency vs Doxycycline in Rosacea
- First Posted Date
- 2014-07-30
- Last Posted Date
- 2022-06-01
- Lead Sponsor
- Centre Hospitalier Universitaire de Nice
- Target Recruit Count
- 20
- Registration Number
- NCT02204254
- Locations
- 🇫🇷
CRC, Hôpital de l'Archet, 151 route de saint-ginestière, Nice, Alpes-maritimes, France
Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis
- First Posted Date
- 2014-06-26
- Last Posted Date
- 2014-12-15
- Lead Sponsor
- CD Pharma India Pvt. Ltd.
- Target Recruit Count
- 30
- Registration Number
- NCT02174757
- Locations
- 🇮🇳
Dept. of Periodontics and Implantology, Sree Mookambika Institute of Dental Sciences, Kulasekharam, Tamil Naidu, India
A Phase II Study of Doxycycline in Relapsed NHL
- Conditions
- Interventions
- First Posted Date
- 2014-03-13
- Last Posted Date
- 2016-12-22
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 7
- Registration Number
- NCT02086591
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers
- Conditions
- Interventions
- First Posted Date
- 2014-01-15
- Last Posted Date
- 2015-05-14
- Lead Sponsor
- Royer Biomedical, Inc.
- Target Recruit Count
- 9
- Registration Number
- NCT02036528
- Locations
- 🇺🇸
GF Professional Research, Corp., Miami Lakes, Florida, United States
🇺🇸Florida Medical Center & Research, Inc., Miami, Florida, United States
🇺🇸Detroit Clinical Research Center, PC, Farmington Hills, Michigan, United States
Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
- Conditions
- Interventions
- First Posted Date
- 2013-12-20
- Last Posted Date
- 2016-05-12
- Lead Sponsor
- Umeå University
- Target Recruit Count
- 55
- Registration Number
- NCT02016365
- Locations
- 🇸🇪
Dept of Clinical Medicin, Ptieå Hospital, Piteå, Sweden
🇸🇪Dept of clinical medicin, Skellefteå Hospital, Skellefteå, Sweden
🇸🇪Dept of Clinical Medicine, Umeå University Hospital, Umeå, Sweden
Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection
- Conditions
- Interventions
- First Posted Date
- 2013-12-09
- Last Posted Date
- 2013-12-09
- Lead Sponsor
- Indian Council of Medical Research
- Target Recruit Count
- 146
- Registration Number
- NCT02005653
- Locations
- 🇮🇳
Vector Control Research Centre, Pondicherry, India
Drug Development Updates
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