Doxycycline

Generic Name
Doxycycline
Brand Names
Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
Drug Type
Small Molecule
Chemical Formula
C22H24N2O8
CAS Number
564-25-0
Unique Ingredient Identifier
334895S862
Background

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...

Indication

Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:

It is also used to treat infections caused by the following gram-negative microorganisms:

Associated Conditions
Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
Associated Therapies
-

Doxycycline for the Prevention of Spontaneous Bacterial Peritonitis

First Posted Date
2019-11-06
Last Posted Date
2024-03-27
Lead Sponsor
Methodist Health System
Target Recruit Count
841
Registration Number
NCT04153604
Locations
🇺🇸

Methodist Dallas Medical Center, Dallas, Texas, United States

Analysis of the Microbiome in Rosacea

Early Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2019-09-30
Last Posted Date
2024-06-06
Lead Sponsor
Johns Hopkins University
Target Recruit Count
150
Registration Number
NCT04108897
Locations
🇺🇸

Cutaneous Translational Research Program, Department of Dermatology, Baltimore, Maryland, United States

Doxycycline PEP for Prevention of Sexually Transmitted Infections Among Kenyan Women Using HIV PrEP

First Posted Date
2019-08-08
Last Posted Date
2024-07-10
Lead Sponsor
University of Washington
Target Recruit Count
449
Registration Number
NCT04050540
Locations
🇰🇪

Kenya Medical Research Institute, Kisumu, Kenya

Tick-borne Encephalitis and Borrelial Antibodies in Serum

First Posted Date
2019-05-20
Last Posted Date
2023-11-29
Lead Sponsor
University Medical Centre Ljubljana
Target Recruit Count
80
Registration Number
NCT03956446
Locations
🇸🇮

University Medical Center Ljubljana, Ljubljana, Slovenia

Treatment and Vaccine Development of Mycoplasma Pneumoniae

Not Applicable
Conditions
Interventions
First Posted Date
2019-04-11
Last Posted Date
2019-04-11
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
100
Registration Number
NCT03911440
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Comparative Efficacy of Single-dose Doxycycline Versus Standard 5- Day Amoxicillin Treatment

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-12-05
Last Posted Date
2018-12-05
Lead Sponsor
Institut de Recherche pour le Developpement
Target Recruit Count
274
Registration Number
NCT03765931
Locations
🇸🇳

Niakhar observational site, Niakhar, Fatick, Senegal

Doxycycline in the Treatment of Aggressive Periodontitis

First Posted Date
2018-11-01
Last Posted Date
2018-11-01
Lead Sponsor
Mohammed V Souissi University
Target Recruit Count
24
Registration Number
NCT03727620
Locations
🇲🇦

BENRACHADI Latifa, Rabat, Morocco

Impact of the Daily Doxycycline Pre-exposure Prophylaxis (PrEP) on the Incidence of Syphilis, Gonorrhoea and Chlamydia

Active, not recruiting
Conditions
First Posted Date
2018-10-17
Last Posted Date
2023-10-05
Lead Sponsor
Kirby Institute
Target Recruit Count
100
Registration Number
NCT03709459
Locations
🇦🇺

Royal Prince Alfred Hospital Sexual Health Medicine, Camperdown, New South Wales, Australia

🇦🇺

Kirketon Road Centre, Sydney, New South Wales, Australia

🇦🇺

Melbourne Sexual Health Centre, Melbourne, Victoria, Australia

and more 1 locations

Lipidome and Microbiome Profile of the Eye in Rosacea

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-08-31
Last Posted Date
2023-09-18
Lead Sponsor
University of California, Davis
Target Recruit Count
30
Registration Number
NCT03655197
Locations
🇺🇸

University of California-Davis, Department of Dermatology, Sacramento, California, United States

Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM

First Posted Date
2018-08-01
Last Posted Date
2021-01-07
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
177
Registration Number
NCT03608774
Locations
🇺🇸

University of Washington - Harborview Medical Center - Center for AIDS and STD, Seattle, Washington, United States

🇺🇸

Fenway Health - The Fenway Institute, Boston, Massachusetts, United States

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