MedPath

Diaminopropanol tetraacetic acid

Generic Name
Diaminopropanol tetraacetic acid
Drug Type
Small Molecule
Chemical Formula
C11H18N2O9
CAS Number
3148-72-9
Unique Ingredient Identifier
949B9ZMO7M
Background

Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.

Drug Eluting Stenting and Short Dual Antiplatelet Therapy for Preventing Recurrent Stroke in Vertebral Stenosis Registry Study

Not yet recruiting
Conditions
Vertebral Artery Stenosis
Interventions
First Posted Date
2024-11-11
Last Posted Date
2024-11-11
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
520
Registration Number
NCT06683300
Locations
🇨🇳

Beijing Tiantan Hospital, Beijing, China

Efficacy and Safety of Shortening Dual Antiplatelet Therapy Duration with IVUS Guidance in PCI Patients

Not Applicable
Not yet recruiting
Conditions
Coronary Arterial Disease (CAD)
Percutaneous Coronary Intervention (PCI)
Intravascular Ultrasound
Dual Antiplatelet Therapy
Interventions
First Posted Date
2024-10-18
Last Posted Date
2024-10-18
Lead Sponsor
University Medical Center Ho Chi Minh City (UMC)
Target Recruit Count
3566
Registration Number
NCT06648720
Locations
🇻🇳

University Medical Center of Ho Chi Minh City, Ho Chi Minh, Vietnam

OCT or Angiography Guided De-escalation of DAPT

Early Phase 1
Not yet recruiting
Conditions
Neointimal Coverage
ST Elevation Myocardial Infarction
Dual Antiplatelet Therapy
Antiplatelet De-escalation
Optical Coherence Tomography
Interventions
Procedure: OCT-guided PCI
Procedure: Conventional angiography-based PCI
First Posted Date
2024-04-01
Last Posted Date
2024-04-01
Lead Sponsor
Shenyang Northern Hospital
Target Recruit Count
80
Registration Number
NCT06339021
Locations
🇨🇳

Northern Hospital, Shenyang, Liaoning, China

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

Phase 4
Recruiting
Conditions
ACS - Acute Coronary Syndrome
CYP2C19 Polymorphism
Interventions
Drug: CYP2C19 Genotype Guided DAPT
First Posted Date
2024-02-28
Last Posted Date
2024-03-20
Lead Sponsor
Zunyi Medical College
Target Recruit Count
1200
Registration Number
NCT06283888
Locations
🇨🇳

Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China

OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time

Not Applicable
Not yet recruiting
Conditions
Acute Coronary Syndrome
Interventions
Drug: OPT-CAD score guided DAPT de-escalation
First Posted Date
2024-01-22
Last Posted Date
2024-01-22
Lead Sponsor
Shenyang Northern Hospital
Target Recruit Count
3490
Registration Number
NCT06216821
Locations
🇨🇳

General Hospital of Northern Theater Command, Shenyang, Liaoning, China

Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus

Phase 4
Recruiting
Conditions
STEMI - ST Elevation Myocardial Infarction
Interventions
Drug: NOAC+DAPT
First Posted Date
2023-08-28
Last Posted Date
2024-03-19
Lead Sponsor
Zunyi Medical College
Target Recruit Count
374
Registration Number
NCT06013020
Locations
🇨🇳

Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China

Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy

Phase 3
Recruiting
Conditions
Coronary Artery Disease
Interventions
First Posted Date
2023-07-19
Last Posted Date
2025-05-16
Lead Sponsor
iVascular S.L.U.
Target Recruit Count
2312
Registration Number
NCT05952206
Locations
🇧🇪

Olv Aalst, Aalst, Belgium

🇧🇪

IMELDA, Bonheiden, Belgium

🇧🇪

CHU Marie Curie, Charleroi, Belgium

and more 36 locations

Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy

Phase 4
Recruiting
Conditions
Anticoagulation
Coronary Endarterectomy
Interventions
First Posted Date
2023-03-23
Last Posted Date
2025-04-04
Lead Sponsor
China National Center for Cardiovascular Diseases
Target Recruit Count
202
Registration Number
NCT05782270
Locations
🇨🇳

Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing, China

PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction

Phase 4
Recruiting
Conditions
ST-segment Elevation Myocardial Infarction (STEMI)
Interventions
First Posted Date
2023-02-02
Last Posted Date
2023-03-01
Lead Sponsor
Kindai University
Target Recruit Count
2258
Registration Number
NCT05709626
Locations
🇯🇵

Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan

Ultrathin-strut Biodegradable Polymer Sirolimus-eluting Stents With P2Y12 Inhibitor-based Single Antiplatelet Therapy vs. Conventional DAPT for Unprotected Left Main Coronary Artery Disease (ULTIMATE-LM)

Not Applicable
Not yet recruiting
Conditions
Left Main Coronary Artery Stenosis
Interventions
Device: LMCA PCI with Supraflex Cruz ultrathin-strut biodegradable polymer sirolimus-eluting stent (Sahajanand Medical Technologies Ltd., Surat, India).
Drug: P2Y12 inhibitor-based SAPT after short DAPT
First Posted Date
2022-12-14
Last Posted Date
2025-02-05
Lead Sponsor
IGLESIAS Juan Fernando
Target Recruit Count
828
Registration Number
NCT05650411
Locations
🇨🇭

Zurich University Hospital, Zürich, Switzerland

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