Derazantinib

Generic Name
Derazantinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C29H29FN4O
CAS Number
1234356-69-4
Unique Ingredient Identifier
N9B0H171MJ
Background

Derazantinib is under investigation in clinical trial NCT03230318 (Derazantinib in Subjects With FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma).

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements

Phase 2
Active, not recruiting
Conditions
Intrahepatic Cholangiocarcinoma
Interventions
Drug: Atezolizumab
Drug: Derazantinib
First Posted Date
2022-01-03
Last Posted Date
2024-07-24
Lead Sponsor
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Target Recruit Count
27
Registration Number
NCT05174650
Locations
🇩🇪

MVZ am Oskar-Helene Heim Berlin, Berlin, Germany

🇩🇪

Universitätsmedizin Mannheim, Mannheim, Germany

🇩🇪

Vivantes Klinikum Berlin Friedrichshain, Berlin, Germany

and more 14 locations

Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma

First Posted Date
2020-10-27
Last Posted Date
2024-04-04
Lead Sponsor
Basilea Pharmaceutica
Target Recruit Count
47
Registration Number
NCT04604132
Locations
🇷🇺

Tomsk Research Instutite of Oncology, Tomsk, Russian Federation

🇪🇸

MD Anderson Cancer Centre, Madrid, Spain

🇧🇷

Liga Norte-Rio-Grandense Contra o Câncer, Natal, Rio Grande Do Norte, Brazil

and more 78 locations

Expanded Access Use of Derazantinib for Advanced Intrahepatic Cholangiocarcinoma (iCCA) With FGFR Genomic Alterations

First Posted Date
2019-09-12
Last Posted Date
2024-08-23
Lead Sponsor
Basilea Pharmaceutica
Registration Number
NCT04087876

Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

First Posted Date
2017-07-26
Last Posted Date
2023-12-19
Lead Sponsor
Basilea Pharmaceutica
Target Recruit Count
148
Registration Number
NCT03230318
Locations
🇧🇪

Antwerp University Hospital, Edegem, Belgium

🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 36 locations
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