Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is not tumour-specific and...
Ofatumumab is indicated, in combination with chlorambucil, for the treatment of previously untreated patients with chronic lymphocytic leukemia (CLL) for whom fludarabine-based therapy is considered inappropriate.
...
Colorado Blood Cancer Institute, Denver, Colorado, United States
Florida Cancer Specialists-North, Saint Petersburg, Florida, United States
Florida Cancer Specialists-South, Fort Myers, Florida, United States
Universitätsklinikum Dresden, Dresden, Sachsen, Germany
Klinikum der Johannes Gutenberg Universität, Mainz, Rheinland-Pfalz, Germany
Klinikum der Universität zu Köln, Köln, Nordrhein-Westfalen, Germany
RCCS_AOU San Martino-IST-Ematologia 1-Monoblocco 11°piano- lato ponente, Genova, Italy
Divisione di Ematologia con trapianto di midollo - A.U. Policlinico "Paolo Giaccone", Palermo, Italy
Dipartimento Emato-Oncologia A.O."Bianchi-Melacrino-Morelli", Reggio Calabria, Italy
Novartis Investigative Site, Morgantown, West Virginia, United States
IRCCS Policlinico San Matteo Pavia Istituto di Ematologia, Pavia, Italy
Presidi Ospedalieri Spedali Civili di Brescia Divisione di Ematologia, Brescia, Italy
Azienda Ospedaliera San Gerardo di Monza U.O. Ematologia, Monza, MB, Italy
University of Minnesota, Minneapolis, Minnesota, United States
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Mayo Clinic Cancer Center, Phoenix, Arizona, United States
Derriford Hospital, Plymouth, Devon, United Kingdom
Torbay Hospital, Torquay, Devon, United Kingdom
Dorset County Hospital, Dorchester, Dorset, United Kingdom
Saint Mary's Regional Cancer Center, Grand Junction, Colorado, United States
Northwest Medical Specialties, Tacoma, Washington, United States
City of Hope, Duarte, California, United States
Woodlands Medical Specialists, Pensacola, Florida, United States
Florida Cancer Specialists North, Saint Petersburg, Florida, United States
Space Coast Cancer Center, Titusville, Florida, United States
H. Morales Meseguer., Murcia, Spain
Hospital Vall d'Hebron, Barcelona, Spain
H.U. La Paz, Madrid, Spain
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.