DeepMed Research

Tinidazole

Generic Name: Tinidazole

Brand Names: Tindamax

Drug Type: Small Molecule

Chemical Formula: C_₈H_₁₃N_₃O_₄S

CAS Number: 19387-91-8

Unique Ingredient Identifier: 033KF7V46H

Background: A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.

Indication: For the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestinal amebiasis and amebic liver abscess caused by E. histolytica in both adults and pediatric patients older than three years of age.

Associated Conditions: Amebiasis, Bacterial Vaginosis (BV), Giardiasis, Mixed Vaginal Infections, Nongonococcal urethritis, Sexually Transmitted Disease (STD), Trichomonas Vaginalis Infection, Trichomonas Vaginitis, Vaginal Candidiasis

Clinical Trials

Safety and Efficacy of Two Oral Tinidazole Regimens for Refractory Trichomonas Vaginitis

Not Applicable

Not yet recruiting

Conditions: Trichomonas Vaginitis

Interventions: Drug: Tinidazole 56
Drug: Tinidazole 42

First Posted Date: 2022-05-20

Last Posted Date: 2024-06-11

Lead Sponsor: Shangrong Fan

Target Recruit Count: 20

Registration Number: NCT05383521

Locations: 🇨🇳
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
🇨🇳
Beijing Obstetrics and Gynecology Hospital,Capital Medical University, Peking, China
🇨🇳
Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Peking, China

and more 1 locations

Effectiveness of Rifabutin for Treatment of Helicobacter Pylori

Phase 3

Conditions: Gastritis H Pylori
Helicobacter Infections
Resistance Bacterial

Interventions: Drug: Rifabutin
Drug: Amoxicillin
Drug: Esomeprazole
Drug: Clarithromycin
Drug: Tinidazole

First Posted Date: 2020-12-03

Last Posted Date: 2021-03-10

Lead Sponsor: Rabin Medical Center

Target Recruit Count: 300

Registration Number: NCT04652284

Helicobacter Pylori Rescue Treatment Containing Tetracycline in Patients Allergic to Penicillin

Phase 4

Conditions: Helicobacter Pylori Infection

Interventions: Drug: Furazolidone
Drug: Tinidazole

First Posted Date: 2020-02-11

Last Posted Date: 2021-11-18

Lead Sponsor: Shandong University

Target Recruit Count: 250

Registration Number: NCT04264663

Locations: 🇨🇳
Qilu hospital, Jinan, Shandong, China

The Epidemiology and Optimal Treatment of Helicobacter Pylori in Myanmar

Phase 4

Completed

Conditions: Helicobacter Pylori Infection

Interventions: Drug: Clarithromycin 500mg
Drug: Amoxicillin 500mg
Drug: Tinidazole 500mg
Drug: Rabeprazole 20mg

First Posted Date: 2019-10-18

Last Posted Date: 2019-10-18

Lead Sponsor: Kirby Institute

Target Recruit Count: 313

Registration Number: NCT04132479

Locations: 🇲🇲
Insein General Hospital, Yangon, Myanmar

Helicobacter Pylori First-line Treatment in Patients Allergic to Penicillin

Phase 4

Conditions: Helicobacter Pylori Infection

Interventions: Drug: tinidazole
Drug: Levofloxacin

First Posted Date: 2019-10-10

Last Posted Date: 2021-11-18

Lead Sponsor: Shandong University

Target Recruit Count: 250

Registration Number: NCT04122287

Locations: 🇨🇳
Qilu hospital, Jinan, Shandong, China

Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men

Not Applicable

Conditions: Foreskin HIV Susceptibility

Interventions: Drug: Oral Tinidazole
Drug: Topical metronidazole
Drug: Topical Clindamycin
Drug: Topical Hydrogen Peroxide

First Posted Date: 2018-01-26

Last Posted Date: 2018-01-26

Lead Sponsor: University of Toronto

Target Recruit Count: 125

Registration Number: NCT03412071

Locations: 🇺🇬
UVRI-IAVI HIV Vaccine Program, Entebbe, Wakiso, Uganda

Antimicrobial Susceptibility Testing Guided Triple Therapy in Salvage Helicobacter Pylori Treatment

Phase 4

Conditions: Antimicrobial Susceptibility Testing
Triple Therapy

Interventions: Drug: amoxicillin
Drug: tinidazole
Drug: clarithromycin
Drug: levofloxacin
Drug: furazolidone
Drug: tetracycline
Drug: Ilaprazole

First Posted Date: 2017-05-03

Last Posted Date: 2017-05-03

Lead Sponsor: Yanqing Li

Target Recruit Count: 120

Registration Number: NCT03139253

Treatment of Giardia Lamblia Infections in Children

Phase 4

Terminated

Conditions: GIARDIASIS

Interventions: Drug: Metronidazole
Drug: Tinidazole

First Posted Date: 2016-10-24

Last Posted Date: 2020-11-18

Lead Sponsor: Helsinki University Central Hospital

Target Recruit Count: 8

Registration Number: NCT02942485

Locations: 🇫🇮
Children's Hospital, HYKS, Helsinki, Finland

Crossover Bioequivalence Study of Tinidazole 500 mg Tablets Under Fed Conditions

Phase 1

Completed

Conditions: Trichomoniasis

Interventions: Drug: Tinidazole

First Posted Date: 2012-05-04

Last Posted Date: 2018-01-23

Lead Sponsor: Roxane Laboratories

Target Recruit Count: 28

Registration Number: NCT01591889

Locations: 🇺🇸
Novum Pharmaceutical Research Services, Houston, Texas, United States

Antiparasitic Treatment for Returning Travelers With Chronic Diarrhea

Not Applicable

Conditions: Chronic Diarrhea
Abdominal Pain
Bloating

Interventions: Drug: Tinidazole and Albendazole
Drug: Placebo control

First Posted Date: 2010-02-18

Last Posted Date: 2014-08-27

Lead Sponsor: Sheba Medical Center

Target Recruit Count: 100

Registration Number: NCT01070277

Locations: 🇮🇱
Sheba Medical Center, Ramat-Gan, Israel
🇮🇱
Chaim Sheba Medical Center, Tel Hashomer, Israel, Ramat Gan, Israel

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy