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Volociximab

Generic Name
Volociximab
Drug Type
Biotech
CAS Number
558480-40-3
Unique Ingredient Identifier
496K5Z02NW
Indication

Investigated for use/treatment in solid tumors, renal cell carcinoma, melanoma, pancreatic cancer, lung cancer, and ovarian cancer.

A Phase 1 Ascending and Parallel Group Trial to Establish the Safety, Tolerability and Pharmacokinetics Profile of Volociximab (Alpha 5 Beta 1 Integrin Antagonist) in Subjects With Neovascular Age- Related Macular Degeneration

Phase 1
Completed
Conditions
Age-related Macular Degeneration
First Posted Date
2008-10-31
Last Posted Date
2024-02-21
Lead Sponsor
Ophthotech Corporation
Target Recruit Count
63
Registration Number
NCT00782093

A Phase 2, Single-Arm Study of Volociximab Monotherapy in Subjects With Platinum-Resistant Advanced Epithelial Ovarian Cancer or Primary Peritoneal Cancer

Phase 2
Terminated
Conditions
Ovarian Cancer
Peritoneal Neoplasms
Interventions
First Posted Date
2007-08-16
Last Posted Date
2012-08-23
Lead Sponsor
Facet Biotech
Target Recruit Count
16
Registration Number
NCT00516841
Locations
🇺🇸

UCI Medical Center, Orange, California, United States

🇺🇸

Sharp Hospital, San Diego, California, United States

🇺🇸

UCLA JCCC Clinical Research Unit, Los Angeles, California, United States

and more 20 locations

A Study of Volociximab in Combination With Gemcitabine in Metastatic Pancreatic Cancer

Phase 2
Completed
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2006-11-20
Last Posted Date
2013-01-30
Lead Sponsor
AbbVie (prior sponsor, Abbott)
Target Recruit Count
40
Registration Number
NCT00401570
Locations
🇬🇧

Site Reference ID/Investigator# 70536, Manchester, United Kingdom

🇬🇧

Site Reference ID/Investigator# 70534, Glasgow, United Kingdom

🇺🇸

Site Reference ID/Investigator# 70538, Pittsburgh, Pennsylvania, United States

and more 3 locations

A Study of Volociximab in Metastatic Melanoma

Phase 2
Terminated
Conditions
Stage IV Melanoma
Interventions
First Posted Date
2006-08-29
Last Posted Date
2012-04-27
Lead Sponsor
Abbott
Target Recruit Count
19
Registration Number
NCT00369395
Locations
🇺🇸

Site Reference ID/Investigator# 70376, Boston, Massachusetts, United States

🇺🇸

Site Reference ID/Investigator# 70356, La Jolla, California, United States

🇺🇸

Site Reference ID/Investigator# 70375, Aurora, Colorado, United States

and more 4 locations

Study of M200 (Volociximab) in Patients With Metastatic Renal Cell Carcinoma (RCC)

Phase 2
Terminated
Conditions
Renal Cell Carcinoma
Metastases
Interventions
First Posted Date
2005-01-05
Last Posted Date
2012-04-27
Lead Sponsor
Abbott
Target Recruit Count
48
Registration Number
NCT00100685
Locations
🇺🇸

Site Reference ID/Investigator# 70400, Los Angeles, California, United States

🇺🇸

Site Reference ID/Investigator# 70399, Cleveland, Ohio, United States

🇺🇸

Site Reference ID/Investigator# 70401, New York, New York, United States

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