MedPath

Zorifertinib

Generic Name
Zorifertinib
Brand Names
泽瑞尼

First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients with Central Nervous System (CNS) Metastases

Phase 2
Completed
Conditions
EGFR Gene Mutation
Non-small Cell Lung Cancer
Brain Metastases
Interventions
First Posted Date
2018-08-31
Last Posted Date
2024-10-15
Lead Sponsor
Alpha Biopharma (Jiangsu) Co., Ltd.
Target Recruit Count
492
Registration Number
NCT03653546
Locations
🇨🇳

China site, Tianjin, China

🇨🇳

China site 0123, Jinan, Shandong, China

🇰🇷

Korea Site, Seoul, Korea, Republic of

and more 3 locations

Phase II Umbrella Study Directed by Next Generation Sequencing

First Posted Date
2018-07-02
Last Posted Date
2022-12-06
Lead Sponsor
Guangdong Association of Clinical Trials
Target Recruit Count
400
Registration Number
NCT03574402
Locations
🇨🇳

Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China

Evaluate Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AZD3759

Phase 1
Completed
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2017-12-04
Last Posted Date
2022-11-25
Lead Sponsor
LYZZ Alpha Holding Ltd
Target Recruit Count
15
Registration Number
NCT03360929
Locations
🇨🇳

0004, Wuhan, Hubei, China

🇨🇳

Guangdong General Hospital, Guangzhou, Guangdong, China

🇨🇳

0003, Hangzhou, Zhejiang, China

and more 1 locations

Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
Interventions
First Posted Date
2014-08-29
Last Posted Date
2021-01-05
Lead Sponsor
AstraZeneca
Target Recruit Count
108
Registration Number
NCT02228369
Locations
🇨🇳

Research Site, Taipei, Taiwan

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