Dantrolene
- Generic Name
- Dantrolene
- Brand Names
- Dantrium, Revonto, Ryanodex, Agilus
- Drug Type
- Small Molecule
- Chemical Formula
- C14H10N4O5
- CAS Number
- 7261-97-4
- Unique Ingredient Identifier
- F64QU97QCR
Overview
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Background
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Indication
For use, along with appropriate supportive measures, for the management of the fulminant hypermetabolism of skeletal muscle characteristic of malignant hyperthermia crises in patients of all ages. Also used preoperatively, and sometimes postoperatively, to prevent or attenuate the development of clinical and laboratory signs of malignant hyperthermia in individuals judged to be malignant hyperthermia susceptible.
Associated Conditions
- Malignant Hyperthermia
- Spasticity
Clinical Trials
FDA Approved Products
Singapore Approved Products
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