Rotavirus vaccine
- Generic Name
- Rotavirus vaccine
- Brand Names
- Rotarix, Rotateq
- Drug Type
- Biotech
Overview
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the 89-12 human strain. Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.
Background
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the 89-12 human strain. Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.
Indication
Rotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks . Rotateq is indicated for the prevention of rotavirus gastroenteritis caused by G1, G2, G3, G4, and G9 types in infants aged 6-32 weeks .
Associated Conditions
- Rotavirus Gastroenteritis caused by rotavirus G1
- Rotavirus Gastroenteritis caused by rotavirus G2
- Rotavirus Gastroenteritis caused by rotavirus G3
- Rotavirus Gastroenteritis caused by rotavirus G4
- Rotavirus Gastroenteritis caused by rotavirus G9
Clinical Trials
FDA Approved Products
Singapore Approved Products
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