Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Associated Conditions
-
Associated Therapies
-

Infrared Lymphangiography as a Method of Sentinel Node Identification

First Posted Date
2014-02-07
Last Posted Date
2017-07-06
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
89
Registration Number
NCT02057393
Locations
πŸ‡ΊπŸ‡Έ

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Single Session Of Antimicrobial Photodynamic Therapy Using Indocyanine Green

First Posted Date
2014-01-23
Last Posted Date
2014-01-23
Lead Sponsor
SVS Institute of Dental Sciences
Target Recruit Count
30
Registration Number
NCT02043340

Near-Infrared Imaging of Peritoneal Carcinomatosis From Colorectal Cancer

First Posted Date
2014-01-10
Last Posted Date
2014-10-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT02032485
Locations
πŸ‡§πŸ‡ͺ

Institut Jules Bordet, Brussels, Belgium

Evaluation of Two Techniques for the SLN Detection in BC Patients

Phase 2
Conditions
Interventions
First Posted Date
2014-01-10
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
214
Registration Number
NCT02032498
Locations
πŸ‡§πŸ‡ͺ

Jules Bordet Institute, Brussels, Belgium

Study of the ICG Distribution in Breast Tumours or in Axillary Lymph Nodes of Patients After Neoadjuvant Therapy

Phase 2
Conditions
Interventions
First Posted Date
2014-01-10
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
20
Registration Number
NCT02032563
Locations
πŸ‡§πŸ‡ͺ

Jules Bordet Institute, Brussels, Belgium

NIR Fluorescence Imaging During Neck Dissection in Head and Neck Cancer Patients After iv Injection of ICG

Phase 2
Conditions
Interventions
First Posted Date
2014-01-06
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT02027831
Locations
πŸ‡§πŸ‡ͺ

Jules Bordet Institute, Brussels, Belgium

Study of the ICG Distribution in the Margins of Breast Cancer After Tumorectomy

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-01-06
Last Posted Date
2023-12-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
20
Registration Number
NCT02027818
Locations
πŸ‡§πŸ‡ͺ

Jules Bordet Institute, Brussels, Belgium

ICG Distribution Using NIF Imaging After IV Injection of ICG in Benign and Malignant Breast Cancer Tissue.

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-11-25
Last Posted Date
2014-10-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT01993576
Locations
πŸ‡§πŸ‡ͺ

Jules Bordet Insitute, Brussels, Belgium

Monocentric Prospective Pilot Study Evaluating the Value of Indocyanine Green (ICG, Indocyanine Green) During a Surgical Resection of Cancerous Lesions Peritoneal Colorectal Origin.

First Posted Date
2013-11-13
Last Posted Date
2015-01-30
Lead Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Target Recruit Count
10
Registration Number
NCT01982227
Locations
πŸ‡«πŸ‡·

CHU de Saint-Etienne, Saint-etienne, France

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