Indocyanine green acid form
- Generic Name
- Indocyanine green acid form
- Brand Names
- Ic-green
- Drug Type
- Small Molecule
- Chemical Formula
- C43H48N2O6S2
- CAS Number
- 28782-33-4
- Unique Ingredient Identifier
- C4V974V932
- Background
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
- Indication
For Determining Cardiac Output, Hepatic Function and Liver Blood Flow
For ophthalmic angiography
Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI)
- Conditions
- Thyroid DiseaseThyroid SurgeryParathyroid Gland
- Interventions
- Device: Parathyroid auto-fluorescence imaging
- First Posted Date
- 2025-04-23
- Last Posted Date
- 2025-04-30
- Lead Sponsor
- OPTOSURGICAL, LLC
- Target Recruit Count
- 64
- Registration Number
- NCT06939946
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
Near-Infrared Fluorescence Imaging with Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery
- Conditions
- Gynecologic CancersOvarian CancerEndometrial CancersCervical CancersVulvar CancerAnastomotic Leaks
- Interventions
- Device: Near-Infrared Fluorescence Imaging System
- First Posted Date
- 2025-03-12
- Last Posted Date
- 2025-03-14
- Lead Sponsor
- Istanbul University
- Target Recruit Count
- 50
- Registration Number
- NCT06871787
- Locations
- 🇹🇷
Istanbul University, Istanbul Faculty of Medicine, Department of Gynecologic Oncology, Istanbul, Turkey
Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis.
- Conditions
- Frozen SectionsIndocyanine GreenBrain Tumor
- Interventions
- Device: cCeLL In vivo
- First Posted Date
- 2025-03-10
- Last Posted Date
- 2025-03-10
- Lead Sponsor
- VPIX Medical
- Target Recruit Count
- 100
- Registration Number
- NCT06867978
Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema
- Conditions
- Breast Cancer-Related LymphedemaBreast Carcinoma
- Interventions
- Procedure: Fluid TherapyOther: Questionnaire AdministrationOther: Research or Clinical Assessment ToolProcedure: SPY Elite Fluorescence ImagingOther: Survey Administration
- First Posted Date
- 2024-11-04
- Last Posted Date
- 2024-11-04
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT06672224
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
Using Indocyanine Green (ICG) to Outline Biliary Tree During Laparoscopic Cholecystectomy
- Conditions
- Chronic Calculous CholecystitisLaparoscopic Cholecystectomy
- Interventions
- Drug: Indocyanine Green Drug
- First Posted Date
- 2024-10-07
- Last Posted Date
- 2024-10-07
- Lead Sponsor
- Theodor Bilharz Research Institute
- Target Recruit Count
- 60
- Registration Number
- NCT06629415
- Locations
- 🇪🇬
Theodor Bilharz Research Institute, Giza, Egypt
Impact of Intraoperative ICG on Functional Outc in RARP
- First Posted Date
- 2024-06-06
- Last Posted Date
- 2024-10-14
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 400
- Registration Number
- NCT06446648
- Locations
- 🇺🇸
Chao Family Comprehensive Cancer Center University of California, Irvine, Orange, California, United States
The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.
- Conditions
- Liver Tumor; Surgery
- First Posted Date
- 2024-05-03
- Last Posted Date
- 2024-05-03
- Target Recruit Count
- 173
- Registration Number
- NCT06398028
- Locations
- 🇪🇸
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Permanence of Indocyanine Green in Axillary Lymph Nodes 3 Weeks After Subdermal Injection in Patients With Breast Cancer and Metastatic Lymph Nodes
- First Posted Date
- 2024-04-04
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Centro di Riferimento Oncologico - Aviano
- Target Recruit Count
- 10
- Registration Number
- NCT06347354
- Locations
- 🇮🇹
Centro di Riferimento Oncologico (CRO) di Aviano - IRCCS, Aviano, Pordenone, Italy
A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
- Conditions
- Breast Cancer
- Interventions
- Procedure: ICG-guided manual lymphatic drainageProcedure: Traditional manual lymphatic drainage
- First Posted Date
- 2024-03-25
- Last Posted Date
- 2025-05-06
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 30
- Registration Number
- NCT06327490
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
ICG Anastomotic Control in Digestive System Surgery
- First Posted Date
- 2024-02-21
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Shandong Linglong Yingcheng Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT06270745
- Locations
- 🇨🇳
Shandong Linglong Yingcheng Hospital, Yantai, Shandong, China
Drug Development Updates
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