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Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract

Not Applicable
Completed
Conditions
Colorectal Polyps
Distal Colonic Lesions
High Risk Polyposis Syndrome
Interventions
First Posted Date
2010-04-28
Last Posted Date
2014-02-24
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
4
Registration Number
NCT01112514
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Advanced Gastrointestinal Endoscopic Imaging

Not Applicable
Terminated
Conditions
Gastrointestinal Diseases
Gastrointestinal Stromal Tumor (GIST)
Gastric (Stomach) Cancer
Interventions
Device: Dual axis endoscopic microscope
Device: wide field fluorescence system
Device: CellVizio
First Posted Date
2009-12-17
Last Posted Date
2024-06-26
Lead Sponsor
Stanford University
Target Recruit Count
3
Registration Number
NCT01034670
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction

Phase 1
Completed
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Lung Cancer
Interventions
Other: high performance liquid chromatography
Other: intracellular fluorescence polarization analysis
Other: liquid chromatography
Other: mass spectrometry
Other: pharmacological study
First Posted Date
2007-10-08
Last Posted Date
2019-03-11
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
47
Registration Number
NCT00540982
Locations
🇺🇸

City of Hope Medical Group, Pasadena, California, United States

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin

Phase 1
Completed
Conditions
Melanoma (Skin)
Metastatic Cancer
First Posted Date
2007-03-28
Last Posted Date
2015-05-06
Lead Sponsor
University of Oklahoma
Target Recruit Count
11
Registration Number
NCT00453050
Locations
🇺🇸

Oklahoma University Cancer Institute, Tulsa, Oklahoma, United States

Insulin on Post Burn Hypermetabolism

Not Applicable
Completed
Conditions
Burns
Interventions
First Posted Date
2005-08-29
Last Posted Date
2012-04-12
Lead Sponsor
United States Army Institute of Surgical Research
Target Recruit Count
14
Registration Number
NCT00137254
Locations
🇺🇸

US Army Institute of Surgical Research, Fort Sam Houston, Texas, United States

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