Indocyanine green acid form
- Generic Name
- Indocyanine green acid form
- Brand Names
- Ic-green
- Drug Type
- Small Molecule
- Chemical Formula
- C43H48N2O6S2
- CAS Number
- 28782-33-4
- Unique Ingredient Identifier
- C4V974V932
- Background
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
- Indication
For Determining Cardiac Output, Hepatic Function and Liver Blood Flow
For ophthalmic angiography
Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT
- Conditions
- CholestasisPrimary Biliary CirrhosisPrimary Sclerosing Cholangitis
- Interventions
- First Posted Date
- 2013-06-18
- Last Posted Date
- 2015-02-23
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 22
- Registration Number
- NCT01879735
- Locations
- π©π°
Department of Nuclear medicine and PET-center, Aarhus, Aarhus C, Denmark
Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque
- Conditions
- AtherosclerosisAtherosclerotic PlaqueCarotid Stenosis
- Interventions
- First Posted Date
- 2013-06-10
- Last Posted Date
- 2017-02-02
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 5
- Registration Number
- NCT01873716
- Locations
- πΊπΈ
Massachusetts General Hospital, Boston, Massachusetts, United States
Lymph Node Mapping in Patients With Endometrial Cancer
- Conditions
- Endometrial Cancer
- Interventions
- Procedure: sentinel lymph node detectionProcedure: sentinel lymph node biopsy
- First Posted Date
- 2013-03-26
- Last Posted Date
- 2023-03-22
- Target Recruit Count
- 204
- Registration Number
- NCT01818739
- Locations
- πΊπΈ
Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut, United States
πΊπΈArthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus, Ohio, United States
Intraoperative Imaging of Breast Cancer With Indocyanine Green
- Conditions
- Invasive Lobular CarcinomaDuctal CarcinomaInvasive Ductal Carcinoma
- Interventions
- First Posted Date
- 2013-02-21
- Last Posted Date
- 2021-01-28
- Lead Sponsor
- Abramson Cancer Center at Penn Medicine
- Target Recruit Count
- 10
- Registration Number
- NCT01796041
- Locations
- πΊπΈ
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer
- Conditions
- Breast Cancer
- Interventions
- Device: SPY Elite ImagingDrug: 99technetium-sulfur colloid radiolabel
- First Posted Date
- 2013-01-18
- Last Posted Date
- 2017-12-11
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 23
- Registration Number
- NCT01771666
- Locations
- πΊπΈ
Stanford University, School of Medicine, Stanford, California, United States
PET/CT and Lymph Node Mapping in Finding Lymph Node Metastasis in Patients With High-Risk Endometrial Cancer
- Conditions
- Malignant Mixed Mesodermal (Mullerian) TumorGrade 3 Endometrial Endometrioid AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Mixed AdenocarcinomaEndometrial Serous Adenocarcinoma
- Interventions
- Procedure: Computed TomographyOther: Laboratory Biomarker AnalysisProcedure: Lymph Node MappingProcedure: LymphadenectomyProcedure: Positron Emission Tomography
- First Posted Date
- 2012-11-29
- Last Posted Date
- 2025-05-09
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 150
- Registration Number
- NCT01737619
- Locations
- πΊπΈ
MD Anderson Regional Care Center-The Woodlands, The Woodlands, Texas, United States
πΊπΈMD Anderson Regional Care Center-Sugar Land, Sugar Land, Texas, United States
πΊπΈThe Woman's Hospital of Texas, Houston, Texas, United States
Lymphatic Mapping for Sentinel Node Identification and Analysis
- First Posted Date
- 2012-08-10
- Last Posted Date
- 2019-08-09
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 30
- Registration Number
- NCT01662752
- Locations
- π¬π§
North West London Hospital, London, UK, United Kingdom
Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green
- First Posted Date
- 2011-04-14
- Last Posted Date
- 2018-02-05
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 10
- Registration Number
- NCT01335893
- Locations
- πΊπΈ
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors
- Conditions
- Stage I Renal Cell CancerStage II Renal Cell CancerRecurrent Renal Cell Cancer
- Interventions
- First Posted Date
- 2011-01-24
- Last Posted Date
- 2017-10-13
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 28
- Registration Number
- NCT01281488
- Locations
- πΊπΈ
City of Hope Medical Center, Duarte, California, United States
Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
- Conditions
- Recurrent Breast CancerStage IA Breast CancerStage II Breast CancerLymphedemaStage IB Breast Cancer
- Interventions
- Radiation: technetium Tc 99m sulfur colloidProcedure: sentinel lymph node biopsyProcedure: axillary lymph node biopsyProcedure: bioimpedance spectroscopyProcedure: quality-of-life assessmentOther: lymphedema management
- First Posted Date
- 2011-01-13
- Last Posted Date
- 2014-08-01
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 4
- Registration Number
- NCT01276054
- Locations
- πΊπΈ
USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States
Drug Development Updates
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