Advanced Gastrointestinal Endoscopic Imaging

Not Applicable

Terminated

Conditions: Gastrointestinal Diseases
Gastrointestinal Stromal Tumor (GIST)
Gastric (Stomach) Cancer

Interventions: Device: Dual axis endoscopic microscope
Device: wide field fluorescence system
Device: CellVizio
Drug: fluorescent Peptide
Drug: fluorescein
Drug: indocyanine green

Registration Number: NCT01034670

Lead Sponsor: Stanford University

Brief Summary: To develop new methods to detect malignant and premalignant conditions of the gastrointestinal tract.

Detailed Description: Not available

Recruitment & Eligibility

Status: TERMINATED

Sex: All

Target Recruitment: 3

Inclusion Criteria

patients be at least 18 years of age,

Either genders

All ethnic backgrounds will be considered.

Patients who are scheduled for endoscopy by one of the investigators will be asked if they are interested in participating in the study.

The study will be open to all patients undergoing endoscopy that do not have exclusion criteria. We will ask all patients if they are participating in any other studies. If they are participating in any other study then we will ask them for more information to determine whether there could be any harm from participating in both studies and if there is then they will not be enrolled.

Exclusion Criteria

Patients with unstable vital signs will not be included.

Study & Design

Study Type: INTERVENTIONAL

Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
endoscopy arm	Dual axis endoscopic microscope	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.
endoscopy arm	wide field fluorescence system	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.
endoscopy arm	CellVizio	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.
endoscopy arm	fluorescent Peptide	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.
endoscopy arm	fluorescein	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.
endoscopy arm	indocyanine green	imaging performed in conjunction with the regularly scheduled endoscopy during which the newer imaging techniques will be used to detect premalignant conditions. includes wide field fluorescence, microscopy, Raman spectroscopy and/or ultrasound.

Primary Outcome Measures

Name	Time	Method
Number of Participants With Successful Imaging of the Mucosa	5 years	Detection of mucosa abnormailities as a first step in the goal of detection of neoplasia

Secondary Outcome Measures