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Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download

Phase 1
Conditions
Lung Neoplasms
Esophageal Lesion
Interventions
Device: Olympus VE2 NIR Imaging System
First Posted Date
2022-04-26
Last Posted Date
2022-04-26
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
45
Registration Number
NCT05346380
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Indocyanine Green Test for Evaluation of Perfusion of Staple Line of the Stomach During Laparoscopic Sleeve Gastrectomy

Completed
Conditions
Diabete Type 2
Obesity, Morbid
Cardiac Disease
Vascular Diseases
First Posted Date
2022-04-20
Last Posted Date
2022-04-20
Lead Sponsor
University of Foggia
Target Recruit Count
1
Registration Number
NCT05337644
Locations
🇮🇹

University of Foggia, Foggia, Italy

SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow

Phase 4
Withdrawn
Conditions
Cubital Tunnel Syndrome
Interventions
First Posted Date
2022-04-18
Last Posted Date
2023-06-29
Lead Sponsor
NYU Langone Health
Registration Number
NCT05332405
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography

Terminated
Conditions
Vascularization
Thyroid Cancer
Hypoparathyroidism
Thyroid
Interventions
Device: SPY Portable Handheld Imaging (SPY-PHI)
First Posted Date
2022-04-14
Last Posted Date
2024-07-05
Lead Sponsor
IRCCS San Raffaele
Target Recruit Count
22
Registration Number
NCT05328076
Locations
🇮🇹

San Raffaele Hospital, Milan, Italy

Effect of CNSI vs. ICG in Lymph Node Tracing During Gastrectomy

Phase 2
Active, not recruiting
Conditions
Gastric Cancer
Interventions
First Posted Date
2022-02-08
Last Posted Date
2023-10-19
Lead Sponsor
Hebei Medical University
Target Recruit Count
96
Registration Number
NCT05229874
Locations
🇨🇳

Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei, China

Indocyanine Green Clearance Test in Liver Transplantation (LivInG)

Not Applicable
Recruiting
Conditions
Hepatic and Hepatobiliary Disorders
Interventions
First Posted Date
2022-02-08
Last Posted Date
2022-03-04
Lead Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Target Recruit Count
162
Registration Number
NCT05228587
Locations
🇮🇹

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)

Phase 1
Recruiting
Conditions
Rheumatoid Arthritis
Interventions
Device: MultiSpectral Imaging System
First Posted Date
2022-01-19
Last Posted Date
2025-03-20
Lead Sponsor
University of Rochester
Target Recruit Count
40
Registration Number
NCT05197530
Locations
🇺🇸

University of Rochester, Rochester, New York, United States

Indocyanine Green Molecular Fluorescence Imaging Technique Using in Diagnosis and Treatment of Primary Liver Cancer

Not Applicable
Recruiting
Conditions
Liver Cancer
Interventions
First Posted Date
2021-12-16
Last Posted Date
2022-02-04
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
348
Registration Number
NCT05160740
Locations
🇨🇳

Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China

Intraoperative Evaluation of Axillary Lymphatics

Not Applicable
Completed
Conditions
Lymphedema
Surgery
Breast Cancer
Interventions
Device: OnLume Imaging System
First Posted Date
2021-10-26
Last Posted Date
2024-11-13
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
9
Registration Number
NCT05094102
Locations
🇺🇸

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States

Clinical Study of Indocyanine Green Displaying Pelvic Nerve in Radical Operation of Cervical Cancer

Early Phase 1
Recruiting
Conditions
Cervical Carcinoma
Interventions
First Posted Date
2021-10-21
Last Posted Date
2022-03-18
Lead Sponsor
Fifth Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
86
Registration Number
NCT05087264
Locations
🇨🇳

FifthSunYetSen, Zhuhai, Guangdong, China

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