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Activated charcoal

Generic Name
Activated charcoal
Brand Names
Actidose, Insta-char
Drug Type
Small Molecule
Chemical Formula
C
CAS Number
64365-11-3
Unique Ingredient Identifier
2P3VWU3H10

Overview

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances. It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. However its effects is rendered poor on some compounds including strong acids or bases, methanol and substances with limited absorptive capacity (including iron, lithium, arsenic). It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. The clinical applications of activated charcoal occured in the early 1800's. While this management for acute poisoning is considered fairly invasive, it is on the World Health Organization's List of Essential Medicines that includes the most important medications needed in a basic health system.

Background

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances. It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. However its effects is rendered poor on some compounds including strong acids or bases, methanol and substances with limited absorptive capacity (including iron, lithium, arsenic). It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. The clinical applications of activated charcoal occured in the early 1800's. While this management for acute poisoning is considered fairly invasive, it is on the World Health Organization's List of Essential Medicines that includes the most important medications needed in a basic health system.

Indication

Used as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.

Associated Conditions

  • Abdominal Cramping
  • Aerophagy
  • Bloating
  • Constipation
  • Delayed Transit Time
  • Flatulence
  • Belching
  • Meteorism

FDA Approved Products

ACTIVATED CHARCOAL
Manufacturer:HF Acquisition Co LLC, DBA HealthFirst
Route:ORAL
Strength:208 mg in 1 mL
Approved: 2020/02/19
NDC:51662-1200
INSTA-CHAR AQUEOUS CHERRY
Manufacturer:VistaPharm, LLC
Route:ORAL
Strength:50 g in 240 mL
Approved: 2023/11/20
NDC:66689-202
Ear Ring
Manufacturer:Deseret Biologicals, Inc.
Route:ORAL
Strength:12 [hp_X] in 1 mL
Approved: 2025/04/22
NDC:43742-2178
INSTA-CHAR AQUEOUS
Manufacturer:VistaPharm, LLC
Route:ORAL
Strength:50 g in 240 mL
Approved: 2023/11/20
NDC:66689-201
INSTA-CHAR SORBITOL
Manufacturer:VistaPharm, LLC
Route:ORAL
Strength:50 g in 240 mL
Approved: 2023/11/20
NDC:66689-203

Singapore Approved Products

NORIT TABLET 125 mg
Manufacturer:PT EAGLE INDO PHARMACEUTICAL LABORATORIES
Form:TABLET
Strength:125 mg
Online:Yes
Approved: 1991/06/03
Approval:SIN06063P
NORIT CAPSULE 200 mg
Manufacturer:NORIT NEDERLAND B.V.
Form:CAPSULE
Strength:200 mg
Online:Yes
Approved: 1991/05/07
Approval:SIN05799P
ULTRACARBON TABLET 250 mg
Manufacturer:Merck Healthcare KGaA
Form:TABLET
Strength:250 mg
Online:Yes
Approved: 1991/05/20
Approval:SIN05853P
CHARCOAL TABLET 200 mg
Manufacturer:CHULIA PHARMA SDN BHD
Form:TABLET
Strength:200 mg
Online:Yes
Approved: 1999/01/07
Approval:SIN10625P

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