Indocyanine green acid form
- Generic Name
- Indocyanine green acid form
- Brand Names
- Ic-green
- Drug Type
- Small Molecule
- Chemical Formula
- C43H48N2O6S2
- CAS Number
- 28782-33-4
- Unique Ingredient Identifier
- C4V974V932
- Background
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
- Indication
For Determining Cardiac Output, Hepatic Function and Liver Blood Flow
For ophthalmic angiography
Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT Surgery
- First Posted Date
- 2021-04-13
- Last Posted Date
- 2025-04-13
- Lead Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
- Target Recruit Count
- 65
- Registration Number
- NCT04842162
- Locations
- 🇫🇷
Gustave Roussy, Villejuif, Val De Marne, France
🇧🇪Institut Jules Bordet, Anderlecht, Belgium
Detection and Delineation of Necrotizing Fasciitis Via a Vascular Perfusion Fluorophore
- First Posted Date
- 2021-04-09
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Dartmouth-Hitchcock Medical Center
- Target Recruit Count
- 15
- Registration Number
- NCT04839302
- Locations
- 🇺🇸
Dartmouth-Hitchock, Lebanon, New Hampshire, United States
Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
- First Posted Date
- 2021-03-05
- Last Posted Date
- 2023-10-24
- Lead Sponsor
- University Hospital, Brest
- Target Recruit Count
- 242
- Registration Number
- NCT04785443
- Locations
- 🇫🇷
CHRU de Brest, Brest, France
Intraoperative Tumor Margin Identification With ICG Dye Imaging
- Conditions
- Malignant NeoplasmBenign Neoplasm
- Interventions
- Device: SPY-PHI
- First Posted Date
- 2021-02-12
- Last Posted Date
- 2025-05-15
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT04752137
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
TumorGlow Intraoperative Molecular Imaging (IMI)
- First Posted Date
- 2021-01-26
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 500
- Registration Number
- NCT04723810
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Indocyanine Green to Visualize Critical View of Safety During Laparoscopic Cholecystectomy for Acute Cholecystitis
- Conditions
- Acute CholecystitisAcute; Cholecystitis, CholedocholithiasisAcute Cholecystitis With Obstruction
- Interventions
- First Posted Date
- 2020-11-12
- Last Posted Date
- 2020-12-16
- Lead Sponsor
- Hamad Medical Corporation
- Target Recruit Count
- 80
- Registration Number
- NCT04624841
- Locations
- 🇶🇦
Hamad General Hospital, Doha, Qatar
The Value of Lymph Node Dissection of Indocyanine Green-guided Near-infrared Fluorescent Imaging in Esophagectomy
- Conditions
- Esophageal CancerIndocyanine Green
- Interventions
- First Posted Date
- 2020-11-04
- Last Posted Date
- 2022-01-25
- Lead Sponsor
- Fujian Medical University Union Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT04615806
- Locations
- 🇨🇳
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
IGG Using in Laparoscopic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Chemotherapy
- Conditions
- Gastric CancerLymph Node Metastases
- Interventions
- First Posted Date
- 2020-11-02
- Last Posted Date
- 2023-09-18
- Lead Sponsor
- Fujian Medical University
- Target Recruit Count
- 240
- Registration Number
- NCT04611997
- Locations
- 🇨🇳
Chang-ming Huang, Fuzhou, Fujian, China
A Study to Evaluate Indocyanine Green Lymphangiography to Improve Lymphadenectomy in Gastric Cancer Patients
- First Posted Date
- 2020-10-19
- Last Posted Date
- 2023-07-19
- Lead Sponsor
- Mayo Clinic
- Registration Number
- NCT04591028
- Locations
- 🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States
To Assess and Compare the Performance Two Approach for Sentinel Lymph Node (SNLD) Biopsy for Endometrial Cancer
- Conditions
- Endometrial CancerIndocyanine GreenSentinel Lymph Node
- Interventions
- First Posted Date
- 2020-08-14
- Last Posted Date
- 2020-08-14
- Lead Sponsor
- Haseki Training and Research Hospital
- Target Recruit Count
- 106
- Registration Number
- NCT04514289
- Locations
- 🇹🇷
Cihan Comba, Istanbul, Sultangazi, Turkey
Drug Development Updates
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