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Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Prospective Evaluation of Near-infrared Fluorescence Imaging Use as a Supportive Tool in Deep Infiltrating Endometriosis Surgery

Phase 2
Completed
Conditions
Pelvic Endometriosis
Endometriosis Outside Pelvis
Interventions
First Posted Date
2019-05-02
Last Posted Date
2020-08-05
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
51
Registration Number
NCT03935165
Locations
🇮🇹

Catholic University of Sacred Heart, Rome, RM, Italy

ICG to Assess Ovarian Perfusion

Early Phase 1
Completed
Conditions
Fibroid Uterus
Endometriosis
Uterine Fibroid
Uterus Myoma
Uterine Adenomyosis
Endometrial Cyst
Uterine Cyst
Interventions
First Posted Date
2019-04-25
Last Posted Date
2023-04-18
Lead Sponsor
Northwestern University
Target Recruit Count
54
Registration Number
NCT03927651
Locations
🇺🇸

259 E Erie - Northwestern, Chicago, Illinois, United States

Does Indocyanine Imaging Scoring Predicts Postoperative Parathormone Levels at 24 Hours After Total Thyroidectomy

Completed
Conditions
Thyroid
Parathyroid; Deficiency
Interventions
First Posted Date
2019-04-10
Last Posted Date
2019-08-20
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
60
Registration Number
NCT03910049
Locations
🇬🇷

1st Propedeutic Department of Surgery, AHEPA University General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

🇬🇷

Unit of Endocrine Surgery, Interbalkan Medical Center, Thessaloniki, Greece, Thessaloniki, Please Enter The State Or Province, Greece

Fluorescent Lymphography-Guided Lymphadenectomy In Laparoscopic Proctectomy

Not Applicable
Conditions
Rectal Cancer
Interventions
First Posted Date
2019-02-26
Last Posted Date
2019-05-14
Lead Sponsor
Fudan University
Target Recruit Count
100
Registration Number
NCT03854890
Locations
🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

Diagnostic Value of ICG in Endometriosis

Early Phase 1
Completed
Conditions
Endometriosis
Near Infrared Fluorescence Imaging
Indocyanine Green (ICG)
Laparoscopy
Interventions
First Posted Date
2019-02-21
Last Posted Date
2020-01-18
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
63
Registration Number
NCT03850158
Locations
🇨🇭

Department of Obstetrics and Gynecology, University Hospital of Bern, Inselspital, Bern, Switzerland

Real-time Navigation for Laparoscope Liver Resections Using Fusion 3D Imaging and Indocyanine Green Fluorescence Imaging

Phase 2
Conditions
Liver Resection
Interventions
Device: Laparoscopic surgical navigation system
First Posted Date
2019-01-22
Last Posted Date
2019-01-22
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
50
Registration Number
NCT03811704
Locations
🇨🇳

Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China

Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging

Phase 4
Completed
Conditions
Lymphedema
Interventions
First Posted Date
2018-07-12
Last Posted Date
2024-12-27
Lead Sponsor
University of Iowa
Target Recruit Count
9
Registration Number
NCT03584633
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG

Not Applicable
Completed
Conditions
Breast Cancer
Sentinel Lymph Node
Interventions
First Posted Date
2018-07-09
Last Posted Date
2021-08-04
Lead Sponsor
Chinese Academy of Sciences
Target Recruit Count
130
Registration Number
NCT03579979
Locations
🇨🇳

Key Laboratory of Molecular Imaging, Chinese Academy of Sciences, Beijing, Beijing, China

Near-infrared Fluorescence Imaging as a Supportive Tool for Localisation of Deep Infiltrating Endometriosis During Laparoscopy

Phase 2
Completed
Conditions
Pelvic Endometriosis
Endometriosis Outside Pelvis
Interventions
First Posted Date
2017-11-06
Last Posted Date
2017-11-06
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
27
Registration Number
NCT03332004
Locations
🇮🇹

Catholic University of Sacred Heart, Rome, Italy

TMTP1-ICG Mapping in Colposcopy-directed Biopsy

Phase 1
Conditions
Cervical Intraepithelial Neoplasia
Interventions
Drug: TMTP1
First Posted Date
2017-10-25
Last Posted Date
2021-06-30
Lead Sponsor
Huazhong University of Science and Technology
Target Recruit Count
40
Registration Number
NCT03321461
Locations
🇨🇳

Tongji Hospital, Tongji Medical Colledge, HUST, Wuhan, Hubei, China

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