Indocyanine green acid form

Generic Name: Indocyanine green acid form

Brand Names: Ic-green

Drug Type: Small Molecule

Chemical Formula: C_₄₃H_₄₈N_₂O_₆S_₂

CAS Number: 28782-33-4

Unique Ingredient Identifier: C4V974V932

Background: Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection ...

Indication: For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Associated Conditions: -

Associated Therapies: -

Clinical Trials

Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients

Phase 2

Completed

Conditions: Breast Cancer

Interventions: Drug: Indocyanine green
Drug: Radioisotope

First Posted Date: 2015-06-24

Last Posted Date: 2023-02-22

Lead Sponsor: National Cancer Center, Korea

Target Recruit Count: 130

Registration Number: NCT02479997

Locations: 🇰🇷
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of

Clinical Application of Near-infrared Fluorescence Guided Localization on Breast Surgery in Breast Cancer

Phase 2

Conditions: Breast Cancer

Interventions: Drug: indocyanine green

First Posted Date: 2015-06-16

Last Posted Date: 2015-06-18

Lead Sponsor: National Cancer Center, Korea

Target Recruit Count: 5

Registration Number: NCT02473159

Locations: 🇰🇷
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of

Early Detection of Lymphedema After Cancer Treatments

Not Applicable

Conditions: Lymphadenectomy
Breast Cancer

Interventions: Drug: Indocyanine Green

First Posted Date: 2015-04-14

Last Posted Date: 2015-04-14

Lead Sponsor: Centre Hospitalier Universitaire Saint Pierre

Target Recruit Count: 120

Registration Number: NCT02415725

Locations: 🇧🇪
CHU St-Pierre - Clinique de Lymphologie, Brussels, Belgium

Lymphatic Occlusion Pressure in Lower Limb

Early Phase 1

Conditions: Lymphatic Function

Interventions: Drug: Indocyanine Green

First Posted Date: 2015-04-01

Last Posted Date: 2015-04-01

Lead Sponsor: Centre Hospitalier Universitaire Saint Pierre

Target Recruit Count: 32

Registration Number: NCT02405559

Locations: 🇧🇪
CHU St-Pierre - Lymphology Clinic of Brussels, Brussels, Belgium

Determining Occlusion Pressure in Lymphatic Vessels

Early Phase 1

Completed

Conditions: Determination of the Occlusion Pressure in Lymphatic Vessels

Interventions: Drug: Indocyanine Green

First Posted Date: 2015-02-10

Last Posted Date: 2015-02-13

Lead Sponsor: Centre Hospitalier Universitaire Saint Pierre

Target Recruit Count: 32

Registration Number: NCT02359578

Locations: 🇧🇪
CHU St-Pierre, Brussels, Belgium

Fluorescence Cholangiography During Cholecystectomy - a RCT

Not Applicable

Completed

Conditions: Gallstones
Cholecystitis

Interventions: Drug: Indocyanine green
Drug: Urografin
Device: Near-infrared illumination
Radiation: X-ray

First Posted Date: 2015-01-26

Last Posted Date: 2024-02-28

Lead Sponsor: Hvidovre University Hospital

Target Recruit Count: 120

Registration Number: NCT02344654

Study Assessing The Interest of Indocyanine Green Fluorescence Imaging With Radioisotope Method For Sentinel Lymph Node Biopsy in Patients With Breast Cancer

Phase 3

Completed

Conditions: Breast Neoplasms

Interventions: Drug: isotope
Drug: indocyanine green

First Posted Date: 2014-10-30

Last Posted Date: 2018-04-09

Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Target Recruit Count: 99

Registration Number: NCT02279108

Locations: 🇫🇷
Centre Hospitalier Universitaire de Saint-Etienne, Saint-Etienne, France

Fluorescence Surgery for Sentinel Node Identification in Melanoma

Not Applicable

Conditions: Melanoma
Lymph Node Metastasis

Interventions: Procedure: Near infra red sentinel node biopsy
Drug: Indocyanine green
Device: Intraoperative Near-Infrared Imaging System

First Posted Date: 2014-05-20

Last Posted Date: 2017-02-02

Lead Sponsor: Barretos Cancer Hospital

Target Recruit Count: 318

Registration Number: NCT02142244

Locations: 🇧🇷
Barretos Cancer Hospital, Barretos, SP, Brazil

ICG Use in Angiography for Nasoseptal Flap Harvest

Not Applicable

Completed

Conditions: Skull Base Neoplasms

Interventions: Drug: indocyanine green

First Posted Date: 2014-04-17

Last Posted Date: 2017-04-17

Lead Sponsor: Ohio State University

Target Recruit Count: 5

Registration Number: NCT02117310

Locations: 🇺🇸
The Ohio State University, Columbus, Ohio, United States

Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research

Not Applicable

Completed

Conditions: Sentinel Lymph Node
Breast Cancer

Interventions: Drug: Indocyanine green
Drug: methylene blue

First Posted Date: 2014-03-12

Last Posted Date: 2018-06-07

Lead Sponsor: Chinese Academy of Sciences

Target Recruit Count: 98

Registration Number: NCT02084784

Locations: 🇨🇳
Key Laboratory of Molecular Imaging, Chinese Academy of Sciences, Beijing, Beijing, China

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