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Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Evaluation of Two Techniques for the SLN Detection in BC Patients

Phase 2
Conditions
Breast Cancer
Interventions
First Posted Date
2014-01-10
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
214
Registration Number
NCT02032498
Locations
🇧🇪

Jules Bordet Institute, Brussels, Belgium

Near-Infrared Imaging of Peritoneal Carcinomatosis From Colorectal Cancer

Phase 2
Completed
Conditions
Colorectal Cancer
Peritoneal Carcinomatosis
Interventions
First Posted Date
2014-01-10
Last Posted Date
2014-10-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT02032485
Locations
🇧🇪

Institut Jules Bordet, Brussels, Belgium

Study of the ICG Distribution in Breast Tumours or in Axillary Lymph Nodes of Patients After Neoadjuvant Therapy

Phase 2
Conditions
Breast Cancer
Interventions
First Posted Date
2014-01-10
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
20
Registration Number
NCT02032563
Locations
🇧🇪

Jules Bordet Institute, Brussels, Belgium

Study of the ICG Distribution in the Margins of Breast Cancer After Tumorectomy

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2014-01-06
Last Posted Date
2023-12-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
20
Registration Number
NCT02027818
Locations
🇧🇪

Jules Bordet Institute, Brussels, Belgium

NIR Fluorescence Imaging During Neck Dissection in Head and Neck Cancer Patients After iv Injection of ICG

Phase 2
Conditions
Head and Neck Cancer
Interventions
First Posted Date
2014-01-06
Last Posted Date
2014-07-24
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT02027831
Locations
🇧🇪

Jules Bordet Institute, Brussels, Belgium

ICG Distribution Using NIF Imaging After IV Injection of ICG in Benign and Malignant Breast Cancer Tissue.

Phase 1
Completed
Conditions
Breast Cancer.
Interventions
First Posted Date
2013-11-25
Last Posted Date
2014-10-15
Lead Sponsor
Jules Bordet Institute
Target Recruit Count
10
Registration Number
NCT01993576
Locations
🇧🇪

Jules Bordet Insitute, Brussels, Belgium

Monocentric Prospective Pilot Study Evaluating the Value of Indocyanine Green (ICG, Indocyanine Green) During a Surgical Resection of Cancerous Lesions Peritoneal Colorectal Origin.

Completed
Conditions
Colorectal Cancer Metastatic
Interventions
First Posted Date
2013-11-13
Last Posted Date
2015-01-30
Lead Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Target Recruit Count
10
Registration Number
NCT01982227
Locations
🇫🇷

CHU de Saint-Etienne, Saint-etienne, France

Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction

Not Applicable
Completed
Conditions
Ductal Carcinoma in Situ - Category
Breast Cancer
Prophylactic Mastectomy
Interventions
Procedure: Inframammary Fold Incision
Procedure: Lateral Radial Incision
Procedure: Inframammary Fold Incision or Lateral Radial Incision
Device: Laser-assisted fluorescence angiography
First Posted Date
2013-10-25
Last Posted Date
2018-04-18
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
79
Registration Number
NCT01969448
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery

Not Applicable
Terminated
Conditions
Stage I Endometrial Carcinoma
Stage II Endometrial Carcinoma
Stage III Endometrial Carcinoma
Stage IV Endometrial Carcinoma
Interventions
Procedure: lymph node mapping
Procedure: sentinel lymph node biopsy
Procedure: therapeutic conventional surgery
Procedure: lymphadenectomy
First Posted Date
2013-09-11
Last Posted Date
2020-08-27
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
58
Registration Number
NCT01939028
Locations
🇺🇸

Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma

Not Applicable
Completed
Conditions
Recurrent Melanoma
Interventions
Drug: Isosulfan blue (ISB)
Diagnostic Test: Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC)
First Posted Date
2013-07-12
Last Posted Date
2017-05-24
Lead Sponsor
Stanford University
Target Recruit Count
50
Registration Number
NCT01898403
Locations
🇺🇸

Stanford University Hospitals and Clinics, Stanford, California, United States

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