Indocyanine green acid form

Generic Name: Indocyanine green acid form

Brand Names: Ic-green

Drug Type: Small Molecule

Chemical Formula: C_₄₃H_₄₈N_₂O_₆S_₂

CAS Number: 28782-33-4

Unique Ingredient Identifier: C4V974V932

Background: Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection ...

Indication: For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Associated Conditions: -

Associated Therapies: -

Clinical Trials

The Effect of Chemoradiotherapy on Gastric Perfusion in Patients With Gastric Cancer.

Phase 4

Terminated

Conditions: Gastric Cancer

Interventions: Drug: Indocyanine green

First Posted Date: 2022-05-02

Last Posted Date: 2024-05-02

Lead Sponsor: Rigshospitalet, Denmark

Target Recruit Count: 11

Registration Number: NCT05354856

Locations: 🇩🇰
Rigshospitalet, Copenhagen, Kbh Ø, Denmark

Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download

Phase 1

Conditions: Lung Neoplasms
Esophageal Lesion

Interventions: Device: Olympus VE2 NIR Imaging System
Drug: Indocyanine green

First Posted Date: 2022-04-26

Last Posted Date: 2022-04-26

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 45

Registration Number: NCT05346380

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow

Phase 4

Withdrawn

Conditions: Cubital Tunnel Syndrome

Interventions: Drug: Indocyanine green

First Posted Date: 2022-04-18

Last Posted Date: 2023-06-29

Lead Sponsor: NYU Langone Health

Registration Number: NCT05332405

Locations: 🇺🇸
NYU Langone Health, New York, New York, United States

Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography

Terminated

Conditions: Vascularization
Thyroid Cancer
Hypoparathyroidism
Thyroid

Interventions: Drug: Indocyanine green
Device: SPY Portable Handheld Imaging (SPY-PHI)

First Posted Date: 2022-04-14

Last Posted Date: 2024-07-05

Lead Sponsor: IRCCS San Raffaele

Target Recruit Count: 22

Registration Number: NCT05328076

Locations: 🇮🇹
San Raffaele Hospital, Milan, Italy

Indocyanine Green Clearance Test in Liver Transplantation (LivInG)

Not Applicable

Recruiting

Conditions: Hepatic and Hepatobiliary Disorders

Interventions: Drug: Indocyanine green

First Posted Date: 2022-02-08

Last Posted Date: 2022-03-04

Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Target Recruit Count: 162

Registration Number: NCT05228587

Locations: 🇮🇹
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

Effect of CNSI vs. ICG in Lymph Node Tracing During Gastrectomy

Phase 2

Active, not recruiting

Conditions: Gastric Cancer

Interventions: Drug: carbon nanoparticles
Drug: Indocyanine green

First Posted Date: 2022-02-08

Last Posted Date: 2023-10-19

Lead Sponsor: Hebei Medical University

Target Recruit Count: 96

Registration Number: NCT05229874

Locations: 🇨🇳
Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei, China

Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)

Phase 1

Recruiting

Conditions: Rheumatoid Arthritis

Interventions: Drug: Indocyanine green
Device: MultiSpectral Imaging System

First Posted Date: 2022-01-19

Last Posted Date: 2024-11-12

Lead Sponsor: University of Rochester

Target Recruit Count: 40

Registration Number: NCT05197530

Locations: 🇺🇸
University of Rochester, Rochester, New York, United States

Intraoperative Evaluation of Axillary Lymphatics

Not Applicable

Completed

Conditions: Lymphedema
Surgery
Breast Cancer

Interventions: Device: OnLume Imaging System
Drug: Indocyanine green

First Posted Date: 2021-10-26

Last Posted Date: 2024-11-13

Lead Sponsor: University of Wisconsin, Madison

Target Recruit Count: 9

Registration Number: NCT05094102

Locations: 🇺🇸
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States

Clinical Study of Indocyanine Green Displaying Pelvic Nerve in Radical Operation of Cervical Cancer

Early Phase 1

Recruiting

Conditions: Cervical Carcinoma

Interventions: Drug: Indocyanine green

First Posted Date: 2021-10-21

Last Posted Date: 2022-03-18

Lead Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University

Target Recruit Count: 86

Registration Number: NCT05087264

Locations: 🇨🇳
FifthSunYetSen, Zhuhai, Guangdong, China

Utility of ICG in Benign Bone Tumors

Early Phase 1

Completed

Conditions: Bone Tumor

Interventions: Drug: Indocyanine Green

First Posted Date: 2021-10-13

Last Posted Date: 2024-05-14

Lead Sponsor: Dartmouth-Hitchcock Medical Center

Target Recruit Count: 2

Registration Number: NCT05075889

Locations: 🇺🇸
Dartmouth-Hitchock, Lebanon, New Hampshire, United States

Drug Development Updates

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