Indocyanine green acid form

Generic Name: Indocyanine green acid form

Brand Names: Ic-green

Drug Type: Small Molecule

Chemical Formula: C_₄₃H_₄₈N_₂O_₆S_₂

CAS Number: 28782-33-4

Unique Ingredient Identifier: C4V974V932

Background: Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication: For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Clinical Trials

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula

Not Applicable

Recruiting

Conditions: Tracheo-Esophageal Fistula with Atresia of Esophagus

Interventions: Drug: Indocyanine green

First Posted Date: 2023-02-21

Last Posted Date: 2025-03-04

Lead Sponsor: Birmingham Women's and Children's NHS Foundation Trust

Target Recruit Count: 20

Registration Number: NCT05735964

Locations: 🇬🇧
Birmingham children's hospital, Birmingham, United Kingdom

Use of Indocyanine Green in Acute Cholecystitis

Phase 4

Recruiting

Conditions: Bile Duct Injury
Acute Cholecystitis

Interventions: Drug: Indocyanine green

First Posted Date: 2023-02-02

Last Posted Date: 2023-09-29

Lead Sponsor: Corporacion Parc Tauli

Target Recruit Count: 440

Registration Number: NCT05709548

Locations: 🇪🇸
Hospital de Vic, Vic, Barcelona, Spain
🇪🇸
Hospital Universitari Parc Tauli, Sabadell, Barcelona, Spain

Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.

Phase 2

Terminated

Conditions: Gastric Adenocarcinoma
Peritoneal Carcinomatosis
Peritoneal Metastases
Gastric Cancer

Interventions: Drug: Indocyanine green

First Posted Date: 2023-01-18

Last Posted Date: 2024-04-02

Lead Sponsor: Laval University

Target Recruit Count: 11

Registration Number: NCT05687617

Locations: 🇨🇦
CIUSSS de l'Est-de-l'Île-de-Montréal, Montréal, Quebec, Canada
🇨🇦
CHU de Québec, Quebec City, Quebec, Canada

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

Phase 3

Recruiting

Conditions: Stage I Uterine Corpus Cancer AJCC v8

Interventions: Procedure: Biospecimen Collection
Procedure: Diagnostic Imaging
Procedure: Excisional Biopsy
Drug: Indocyanine Green Solution
Procedure: Minimally Invasive Surgery
Procedure: Pelvic Lymphadenectomy
Other: Questionnaire Administration
Procedure: Sentinel Lymph Node Mapping

First Posted Date: 2022-12-12

Last Posted Date: 2024-07-15

Lead Sponsor: NRG Oncology

Target Recruit Count: 428

Registration Number: NCT05646316

Locations: 🇺🇸
Fairview Southdale Hospital, Edina, Minnesota, United States
🇺🇸
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois, United States
🇺🇸
Parkland Memorial Hospital, Dallas, Texas, United States

and more 38 locations