Indocyanine green acid form

Generic Name: Indocyanine green acid form

Brand Names: Ic-green

Drug Type: Small Molecule

Chemical Formula: C_₄₃H_₄₈N_₂O_₆S_₂

CAS Number: 28782-33-4

Unique Ingredient Identifier: C4V974V932

Background: Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication: For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Clinical Trials

Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity Using Advanced Imaging Modality Arthroscopy

Phase 1

Recruiting

Conditions: Rotator Cuff Tears

Interventions: Drug: Indocyanine Green

First Posted Date: 2020-04-09

Last Posted Date: 2023-11-08

Lead Sponsor: NYU Langone Health

Target Recruit Count: 30

Registration Number: NCT04340752

Locations: 🇺🇸
NYU Langone Health, New York, New York, United States

Sentinel Lymph Node Navigation Surgery Using Near-infrared Imaging in Early Esophageal Cancer

Phase 1

Conditions: Detection Rate of SLN ; Accuracy Rate of Lymph Node Metastasis

Interventions: Drug: Indocyanine Green for Injection

First Posted Date: 2019-11-22

Last Posted Date: 2021-02-24

Lead Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University

Target Recruit Count: 84

Registration Number: NCT04173676

Locations: 🇨🇳
The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China

Indocyanine Green (ICG) Guided Tumor Resection

Phase 1

Recruiting

Conditions: Neoplastic Disease
Solid Tumor

Interventions: Drug: Indocyanine Green

First Posted Date: 2019-09-10

Last Posted Date: 2025-05-18

Lead Sponsor: St. Jude Children's Research Hospital

Target Recruit Count: 230

Registration Number: NCT04084067

Locations: 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

3D Printing for Nodule Localization

Not Applicable

Completed

Conditions: Pulmonary Nodule, Solitary
Lung Cancer

Interventions: Procedure: 3D-printing guided
Procedure: CT-guided
Drug: Methylene blue
Drug: Indocyanine Green
Procedure: Intraoperative
Procedure: Preoperative

First Posted Date: 2019-08-14

Last Posted Date: 2019-08-14

Lead Sponsor: Wen-zhao ZHONG

Target Recruit Count: 47

Registration Number: NCT04056923

Locations: 🇨🇳
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China

Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport

Phase 1

Completed

Conditions: Rheumatoid Arthritis

Interventions: Drug: Indocyanine Green
Device: MultiSpectral Imaging System

First Posted Date: 2019-08-06

Last Posted Date: 2020-09-04

Lead Sponsor: University of Rochester

Target Recruit Count: 2

Registration Number: NCT04046146

Locations: 🇺🇸
University of Rochester, Rochester, New York, United States

The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.

Not Applicable

Completed

Conditions: Intestinal Atresia
Necrotizing Enterocolitis
Hirschsprung Disease
Gastroschisis
Intestinal Obstruction
Incarcerated Hernia
Intussusception
Malrotation
Volvulus
Meconium Ileus