Vinorelbine
- Generic Name
- Vinorelbine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C45H54N4O8
- CAS Number
- 71486-22-1
- Unique Ingredient Identifier
- Q6C979R91Y
- Background
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC .
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- Indication
Vinorelbine tartrate is indicated for adults in the treatment of advanced non-small cell lung cancer (NSCLC), as a single therapy or in combination with other chemotherapeutic drugs .
Used in relapsed or refractory Hodgkin lymphoma, in combination with other chemotherapy agents .
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- Associated Conditions
- Locally Advanced Non-Small Cell Lung Cancer, Metastatic Breast Cancer, Metastatic Cervical Cancer, Metastatic Non-Small Cell Lung Cancer, Recurrent Cervical Cancer, Soft Tissue Sarcoma
- Associated Therapies
- -
Pazopanib + Vinorelbine in Non Small Cell Lung Cancer (NSCLC) and Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2010-02-02
- Last Posted Date
- 2013-10-30
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 8
- Registration Number
- NCT01060514
- Locations
- 🇺🇸
Northwestern University, Northwestern Medical Faculty Foundation, Chicago, Illinois, United States
First-Line Chemotherapy and Panitumumab in Advanced Non-Small Cell Lung Cancer
- Conditions
- First Posted Date
- 2009-12-23
- Last Posted Date
- 2014-12-04
- Lead Sponsor
- Vejle Hospital
- Target Recruit Count
- 23
- Registration Number
- NCT01038037
- Locations
- 🇩🇰
Vejle Hospital, Vejle, Denmark
Concomitant Radio-chemotherapy in the Elderly
- Conditions
- Interventions
- First Posted Date
- 2009-12-10
- Last Posted Date
- 2018-05-03
- Lead Sponsor
- University Hospital, Limoges
- Target Recruit Count
- 48
- Registration Number
- NCT01029678
- Locations
- 🇫🇷
CHU Reims, Reims, France
🇫🇷CH de Meaux, Meaux, France
🇫🇷CHU Brest, Brest, France
Cetuximab in Combination With Chemotherapy for Patients With Head and Neck Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-11-26
- Last Posted Date
- 2020-11-02
- Lead Sponsor
- Per Pfeiffer
- Registration Number
- NCT01020864
- Locations
- 🇩🇰
Department of Oncology, Odense University Hospital, Odense, Denmark
Lapatinib in Combination With Vinorelbine
- First Posted Date
- 2009-11-16
- Last Posted Date
- 2017-05-31
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 112
- Registration Number
- NCT01013740
- Locations
- 🇪🇸
Novartis Investigative Site, Zamora, Spain
Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-11-04
- Last Posted Date
- 2017-04-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 569
- Registration Number
- NCT01007942
- Locations
- 🇺🇸
University of Arizona / Cancer Center AZ Onc Assoc, Tucson, Arizona, United States
🇺🇸Florida Cancer Specialists DeptofFloridaCancerSpecialists, Fort Myers, Florida, United States
🇺🇸Memorial Hospital Memorial Cancer Institute, Hollywood, Florida, United States
Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors
- Conditions
- Interventions
- First Posted Date
- 2009-08-13
- Last Posted Date
- 2018-06-28
- Lead Sponsor
- Puma Biotechnology, Inc.
- Target Recruit Count
- 6
- Registration Number
- NCT00958724
- Locations
- 🇯🇵
Shizuoka Cancer Center, Shizuoka, Japan
🇯🇵The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan
Navelbine And Radiotherapy in Locally Advanced Lung Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-04-24
- Last Posted Date
- 2022-05-17
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 117
- Registration Number
- NCT00887783
- Locations
- 🇩🇰
Department of Oncology, Aalborg University Hospital, Aalborg, Denmark
🇩🇰Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark
🇩🇰Department of Oncology, Odense University Hospital, Odense, Denmark
Capecitabine and Bevacizumab ± Vinorelbine in Metastatic Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2009-03-25
- Last Posted Date
- 2016-08-31
- Lead Sponsor
- iOMEDICO AG
- Target Recruit Count
- 600
- Registration Number
- NCT00868634
- Locations
- 🇩🇪
Onkologische Schwerpunktpraxis Eppendorf, Hamburg, Germany
Efficacy , Safety of Treatment R NIMP for Relapsed Aggressive Lymphomas
- Conditions
- Interventions
- First Posted Date
- 2009-02-12
- Last Posted Date
- 2013-07-24
- Lead Sponsor
- French Innovative Leukemia Organisation
- Target Recruit Count
- 50
- Registration Number
- NCT00842595
- Locations
- 🇫🇷
Hôpital COCHIN, Paris, France
Drug Development Updates
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