Promethazine

Generic Name
Promethazine
Brand Names
Phenadoz, Phenergan, Promethazine DM, Promethegan
Drug Type
Small Molecule
Chemical Formula
C17H20N2S
CAS Number
60-87-7
Unique Ingredient Identifier
FF28EJQ494
Background

Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.
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Indication

Promethazine tablets and suppositories are indicated to treat rhinitis, allergic conjunctivitis, allergic reactions to blood or plasma, dermographism, anaphylactic reactions, sedation, nausea, vomiting, pain, motion sickness, and allergic skin reactions. Promethazine cough syrup with phenylephrine and codeine is indicated to relieve cough and upper respirato...

Associated Conditions
Allergic Conjunctivitis (AC), Allergic urticaria, Anaphylaxis, Cough, Dermographism, Motion Sickness, Nasal Congestion, Postoperative pain, Seasonal Allergic Rhinitis, Vasomotor Rhinitis, Acute Allergic Reactions, Dry cough, Perioperative nausea and vomiting, Upper respiratory symptoms
Associated Therapies
Sedative therapy, Adjunct to anesthesia and analgesia therapy
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