Vitamin E

Generic Name
Vitamin E
Brand Names
Mvc-fluoride, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C29H50O2
CAS Number
59-02-9
Unique Ingredient Identifier
N9PR3490H9
Background

In 1922, vitamin E was demonstrated to be an essential nutrient. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage. The antioxidant effects are currently being researched for use in th...

Indication

Vitamin E supplementation is indicated for treatment of vitamin E deficiency which can occur in cystic fibrosis, cholestasis and severe liver disease, abetalipoproteinemia or simply poor diet.

Associated Conditions
Vitamin Deficiency
Associated Therapies
Long-chain omega-3 fatty acid supplementation, Dietary supplementation
Clinical Trials
Related News

Vitamin E to Treat Uveitis-Associated Macular Edema

Phase 1
Completed
Conditions
Cystoid Macular Edema
Uveitis
First Posted Date
2001-07-27
Last Posted Date
2008-03-04
Lead Sponsor
National Eye Institute (NEI)
Target Recruit Count
80
Registration Number
NCT00021645
Locations
🇺🇸

National Eye Institute (NEI), Bethesda, Maryland, United States

Effect of High Dose Vitamin E on Carotid Atherosclerosis

Phase 2
Completed
Conditions
Cardiovascular Diseases
First Posted Date
2001-02-05
Last Posted Date
2013-03-22
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
120
Registration Number
NCT00010699
Locations
🇺🇸

University of California Davis Medical Center, Sacramento, California, United States

🇺🇸

UC Davis Medical Center, Sacramento, California, United States

Double-Blind, Placebo-Controlled Trial of Vitamin E as Add-on Therapy for Children With Epilepsy

Phase 4
Completed
Conditions
Epilepsy
First Posted Date
2000-02-24
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Registration Number
NCT00004637
Locations
🇺🇸

The Children's Hospital, Neurology B155, Denver, Colorado, United States

Memory Impairment Study (Mild Cognitive Impairment Study)

Phase 3
Completed
Conditions
Alzheimer Disease
First Posted Date
1999-11-01
Last Posted Date
2009-12-11
Lead Sponsor
National Institute on Aging (NIA)
Registration Number
NCT00000173
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

🇺🇸

Baumel-Eisner Neuromedical Institute, Boca Raton, Boca Raton, Florida, United States

and more 69 locations

Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up

First Posted Date
1999-10-28
Last Posted Date
2013-12-13
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000600

Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer

First Posted Date
1999-10-28
Last Posted Date
2012-06-15
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
39876
Registration Number
NCT00000479

Arterial Disease Multifactorial Intervention Trial (ADMIT)

First Posted Date
1999-10-28
Last Posted Date
2016-07-12
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000539

Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

First Posted Date
1999-10-28
Last Posted Date
2020-07-15
Lead Sponsor
Brigham and Women's Hospital
Registration Number
NCT00000541

Women's Angiographic Vitamin and Estrogen Trial (WAVE)

First Posted Date
1999-10-28
Last Posted Date
2016-07-12
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000555

Randomized Trials of Vitamin Supplements and Eye Disease

First Posted Date
1999-09-24
Last Posted Date
2005-06-24
Lead Sponsor
National Eye Institute (NEI)
Registration Number
NCT00000161
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