Trospium

Generic Name
Trospium
Brand Names
Trosec
Drug Type
Small Molecule
Chemical Formula
C25H30NO3
CAS Number
47608-32-2
Unique Ingredient Identifier
T4Y8ORK057
Background

Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by Indevus Pharmaceutical Inc. and was granted FDA...

Indication

For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency, detrusor instability and frequency of micturition.

Associated Conditions
Overactive Bladder Syndrome (OABS)
Associated Therapies
-

Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls

First Posted Date
2023-05-30
Last Posted Date
2024-12-20
Lead Sponsor
The University of Texas Medical Branch, Galveston
Target Recruit Count
48
Registration Number
NCT05880862
Locations
🇺🇸

University of Texas Medical Branch at Galveston, Galveston, Texas, United States

Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

First Posted Date
2020-01-13
Last Posted Date
2024-12-11
Lead Sponsor
Becky Clarkson
Target Recruit Count
220
Registration Number
NCT04227184
Locations
🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:

First Posted Date
2018-10-17
Last Posted Date
2023-10-12
Lead Sponsor
Mansoura University
Target Recruit Count
200
Registration Number
NCT03709992
Locations
🇪🇬

Ahmed R EL-Nahas, Mansoura, Kuwait, Egypt

Treatment Persistence Among Patients With Overactive Bladder: A Retrospective Secondary Data Analysis in Asia Oceania

First Posted Date
2018-07-27
Last Posted Date
2024-10-16
Lead Sponsor
Astellas Pharma Singapore Pte. Ltd.
Target Recruit Count
5589
Registration Number
NCT03602508
Locations
🇦🇺

Site AU10000, Sydney, Australia

🇰🇷

Site KR82001, Seoul, Korea, Republic of

A Registry Study of Patients Initiating a Course of Drug Therapy for Overactive Bladder in Taiwan, Korea and China

First Posted Date
2018-06-28
Last Posted Date
2020-04-22
Lead Sponsor
Astellas Pharma Singapore Pte. Ltd.
Target Recruit Count
805
Registration Number
NCT03572231
Locations
🇰🇷

Site KR410008, Daejeon, Korea, Republic of

🇰🇷

Site KR410009, Incheon, Korea, Republic of

🇰🇷

Site KR410005, Kangam, Korea, Republic of

and more 12 locations

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

First Posted Date
2016-07-13
Last Posted Date
2017-04-19
Lead Sponsor
Karuna Therapeutics
Target Recruit Count
70
Registration Number
NCT02831231
Locations
🇺🇸

Medpace, Cincinnati, Ohio, United States

The Effect of Anticholinergics on Cognitive Function in the Elderly

First Posted Date
2013-08-14
Last Posted Date
2017-03-22
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
59
Registration Number
NCT01922115
Locations
🇺🇸

Unc Chapel Hill Urogynecology A2 Clinic, Chapel Hill, North Carolina, United States

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial

First Posted Date
2010-08-10
Last Posted Date
2016-02-26
Lead Sponsor
Allergan
Target Recruit Count
20
Registration Number
NCT01178827

Anticholinergic vs. Botox Comparison Study

First Posted Date
2010-07-21
Last Posted Date
2018-05-02
Lead Sponsor
NICHD Pelvic Floor Disorders Network
Target Recruit Count
249
Registration Number
NCT01166438
Locations
🇺🇸

Loyola University Medical Center, Maywood, Illinois, United States

🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

🇺🇸

Magee-Women's Hospital, Pittsburgh, Pennsylvania, United States

and more 8 locations

Efficacy of Sanctura XR (Trospium Chloride) for Reducing Overactive Bladder Symptoms in Female Subjects Refractory to Detrol LA (Tolterodine Tartrate Extended Release) Daily

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-03-19
Last Posted Date
2013-09-26
Lead Sponsor
Allergan
Target Recruit Count
322
Registration Number
NCT01089751
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