Motixafortide
- Generic Name
- Motixafortide
- Brand Names
- Aphexda
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 664334-36-5
- Unique Ingredient Identifier
- DA9G065962
- Background
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the pat...
- Indication
Motixafortide is indicated for use in combination with filgrastim to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with multiple myeloma.
- Associated Conditions
- -
- Associated Therapies
- Mobilization of hematopoietic stem cells
Phase II study of novel CXCR2 agonist and Plerixafor for rapid stem cell mobilization in ...
Article references discuss various therapies, transplantation methods, and maintenance strategies for myeloma, including triplet therapy, lenalidomide-bortezomib-dexamethasone with transplantation, and plerixafor-G-CSF for stem cell mobilization.
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