MedPath

Ascrinvacumab

Generic Name
Ascrinvacumab
Drug Type
Biotech
CAS Number
1463459-96-2
Unique Ingredient Identifier
716FQ5REVO
Background

Ascrinvacumab has been used in trials studying the treatment and basic science of Neoplasms, Advanced Solid Tumors, Carcinoma, Hepatocellular, and Malignant Pleural Mesothelioma.

GT90001 Plus Nivolumab in Patients With Advanced Hepatocellular Carcinoma

Phase 2
Active, not recruiting
Conditions
HCC
Hepatocellular Carcinoma
Interventions
First Posted Date
2022-01-05
Last Posted Date
2024-02-22
Lead Sponsor
Suzhou Kintor Pharmaceutical Inc,
Target Recruit Count
5
Registration Number
NCT05178043
Locations
๐Ÿ‡บ๐Ÿ‡ธ

NYU Langone Health, New York, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Los Angeles Hematology Oncology Medical Group, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

City of Hope National Medical Center, Duarte, California, United States

and more 2 locations

A Study To Evaluate The Efficacy And Safety of The Investigational Drug PF-03446962 (A Monoclonal Antibody With Antiangiogenic Features) In Combination With Best Supportive Care Versus Placebo Plus Best Supportive Care In Patients Affected By Recurrent Liver Cancer

Phase 2
Terminated
Conditions
Carcinoma, Hepatocellular
Interventions
Other: Placebo
Other: Best Supportive Care
First Posted Date
2013-07-30
Last Posted Date
2015-10-28
Lead Sponsor
Pfizer
Target Recruit Count
3
Registration Number
NCT01911273
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

Kinki University Hospital, Department of Gastroenterology and Hepatology, Osaka-Sayama, Osaka, Japan

๐Ÿ‡ฏ๐Ÿ‡ต

National Cancer Center Hospital East, Kashiwa, Chiba, Japan

๐Ÿ‡บ๐Ÿ‡ธ

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

and more 1 locations

PF-03446962 in Relapsed or Refractory Urothelial Cancer

Phase 2
Completed
Conditions
Transitional Cell Carcinoma of Bladder
Interventions
First Posted Date
2012-06-15
Last Posted Date
2021-05-14
Lead Sponsor
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Target Recruit Count
14
Registration Number
NCT01620970
Locations
๐Ÿ‡ฎ๐Ÿ‡น

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

A Phase II Study of PF-03446962 in Patients With Advanced Malignant Pleural Mesothelioma

Phase 2
Completed
Conditions
Malignant Pleural Mesothelioma
Interventions
First Posted Date
2011-12-06
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
17
Registration Number
NCT01486368
Locations
๐Ÿ‡จ๐Ÿ‡ฆ

CancerCare Manitoba, Winnipeg, Manitoba, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

BCCA - Vancouver Cancer Centre, Vancouver, British Columbia, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

Cross Cancer Institute, Edmonton, Alberta, Canada

and more 4 locations

Asian Phase I Study Of PF-03446962

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2011-04-18
Last Posted Date
2015-10-28
Lead Sponsor
Pfizer
Target Recruit Count
36
Registration Number
NCT01337050
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

National Cancer Center Hospital East, Kashiwa, Chiba, Japan

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul National University Hospital/Department of Internal Medicine, Seoul, Korea, Republic of

A First In Patient, Study Of Investigational Drug PF-03446962 In Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2007-11-14
Last Posted Date
2015-10-19
Lead Sponsor
Pfizer
Target Recruit Count
70
Registration Number
NCT00557856
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States

๐Ÿ‡ฎ๐Ÿ‡น

S.C Diagnostica Radiologica 2, Milano, Italy

๐Ÿ‡ฎ๐Ÿ‡น

S.C. Chirurgia Generale Indirizzo Oncologico 1 (epato-gastro-pancreatica), Milano, Italy

and more 7 locations
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