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Alpha-1-proteinase inhibitor

Generic Name
Alpha-1-proteinase inhibitor
Brand Names
Aralast, Glassia, Prolastin, Prolastin-C, Respreeza, Zemaira
Drug Type
Biotech
Chemical Formula
-
CAS Number
9041-92-3
Unique Ingredient Identifier
F43I396OIS
Background

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

Indication

For chronic augmentation and maintenance therapy in individuals with alpha1-proteinase inhibitor (A1-PI) deficiency and clinical evidence of emphysema.

Associated Conditions
Emphysema
Associated Therapies
Augmentation, Maintenance therapy

A Research Trial of Aralast NP in New Onset Diabetes (RETAIN) - Part II

Phase 2
Withdrawn
Conditions
Diabetes Mellitus, Type 1
Interventions
Drug: Aralast NP
Drug: Placebo
First Posted Date
2010-08-17
Last Posted Date
2014-12-31
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Registration Number
NCT01183455
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

University of Maryland Medical Center, Baltimore, Maryland, United States

and more 12 locations
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