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Magnesium gluconate

Generic Name
Magnesium gluconate
Drug Type
Small Molecule
Chemical Formula
C12H26MgO16
CAS Number
59625-89-7
Unique Ingredient Identifier
T42NAD2KHC

Overview

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids and laxatives) . Although magnesium is available in the form of sulphates, lactate, hydroxide, oxide and chloride, only magnesium gluconate is recommended for magnesium supplementation as it appears to be better absorbed and causes less diarrha . This drug has been studied in the prevention of pregnancy-induced hypertension, and has displayed promising results . In addition, it has been studied for its effects on premature uterine contractions .

Background

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids and laxatives) . Although magnesium is available in the form of sulphates, lactate, hydroxide, oxide and chloride, only magnesium gluconate is recommended for magnesium supplementation as it appears to be better absorbed and causes less diarrha . This drug has been studied in the prevention of pregnancy-induced hypertension, and has displayed promising results . In addition, it has been studied for its effects on premature uterine contractions .

Indication

Magnesium gluconate is a mineral supplement which is used to prevent and treat low levels of magnesium. Magnesium is very important for the normal physiologic functioning of cells, nerves, muscles, bones, and the heart. Generally, a well-balanced diet provides the necessary amounts of magnesium for homeostasis. However, certain conditions causing chronic magnesium deficiency may decrease levels of magnesium. These conditions include treatment with diuretics, a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes) .

Associated Conditions

No associated conditions information available.

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2000/12/07
Not Applicable
Completed
National Center for Research Resources (NCRR)

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code
ORAL
10 [hp_X] in 1 mL
2025/05/22
70321-0003

EMA Approved Products

Medicine Name
EMA Number
Auth. Holder
Country
Drug Type
Status
Issued
Opinion
Revision

No EMA products found

No EMA products found for this drug

HSA Approved Products

Product Name
Manufacturer
Dosage Form
Strength
Approved
Approval No.
INJECTION
0.7 g/l
2001/11/16
SIN11718P
INJECTION, EMULSION
2.47g /1000ml
2013/01/08
SIN14287P
INJECTION, EMULSION
2.47g /1000ml
2013/01/08
SIN14286P
INJECTION
0.96 g/1000 ml
2001/09/04
SIN11657P

NMPA Approved Products

Product Name
Approval No.
Manufacturer
Dosage Form
Trade Name
Strength
Type
Status
Date
Import
国药准字H20030928
颗粒剂
包乐
5g:3g(以无水葡萄糖酸镁计)
Chemical Drug
Approved
2020/03/31
Domestic

PPB Approved Products

Product Name
Registration Code
Company
Category
Sale Type
Reg. Date

No PPB products found

No PPB products found for this drug

TGA Approved Products

Product Name
ARTG ID
Sponsor
Status
Reg. Date
Ingredient
294446
Active
2017/09/28
magnesium gluconate
232976
Active
2015/01/20
magnesium gluconate
123991
Active
2005/12/05
magnesium gluconate
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