Zinc sulfate

Generic Name: Zinc sulfate

Brand Names: Anodan-HC, Anusol, Egozinc, Multitrace-4, Multitrace-5, Proctodan-HC, Rectogel, Riva-sol HC, Tandem Plus

Drug Type: Small Molecule

Chemical Formula: O_₄SZn

CAS Number: 7733-02-0

Unique Ingredient Identifier: 0J6Z13X3WO

Background: Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Indication: This medication is a mineral used to treat or prevent low levels of zinc alone and together with oral rehydration therapy (ORT). It is also used as a topical astringent. Zinc Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for TPN.

Associated Conditions: Dry Eyes, Local itching, Localized pain, Localized swelling

Associated Therapies: Nutritional supplementation

Clinical Trials

Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2)

Phase 2

Not yet recruiting

Conditions: Sickle Cell Disease

Interventions: Drug: Placebo
Drug: zinc sulfate

First Posted Date: 2024-08-19

Last Posted Date: 2024-08-19

Lead Sponsor: Indiana University

Target Recruit Count: 100

Registration Number: NCT06561061

Efficacy Of Zinc Towards The Outcome on Children With Sepsis

Not Applicable

Completed

Conditions: Sepsis

Interventions: Drug: Placebo
Drug: Zinc Sulfate

First Posted Date: 2024-08-16

Last Posted Date: 2024-08-16

Lead Sponsor: dr. Aldora Jesslyn Oentari

Target Recruit Count: 140

Registration Number: NCT06556511

Locations: 🇮🇩
Hasanuddin University, Makassar, South Sulawesi, Indonesia

Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia

Phase 4

Not yet recruiting

Conditions: Neonatal Hyperbilirubinemia

Interventions: Drug: Zinc sulfate
Drug: Ursodeoxycholic acid

First Posted Date: 2024-07-24

Last Posted Date: 2024-08-09

Lead Sponsor: Amira Adel Fouly

Target Recruit Count: 80

Registration Number: NCT06517862

Locations: 🇪🇬
Neonatal Intensive Care Unit (NICU) of Ain Shams University Hospitals, Cairo, Egypt

Effect of N-acetyl Cysteine and Zinc in Management of Head and Neck Cancer Radiotherapy Induced Oral Mucositis

Phase 2

Completed

Conditions: Radiation-Induced Mucositis

Interventions: Drug: N-acetyl cysteine
Drug: saline mouth wash
Drug: Zinc sulfate

First Posted Date: 2024-07-01

Last Posted Date: 2024-12-31

Lead Sponsor: Mansoura University

Target Recruit Count: 50

Registration Number: NCT06482034

Locations: 🇪🇬
Mansoura university, Mansoura, Egypt

Enteral Zinc Supplementation in Very Low Birth Weight Infants

Phase 3

Not yet recruiting

Conditions: Very Low Birth Weight Infant
Nutritional Deficiency

Interventions: Other: Sterile Water
Drug: Zinc Sulfate

First Posted Date: 2024-05-30

Last Posted Date: 2024-06-06

Lead Sponsor: University of Tennessee

Target Recruit Count: 50

Registration Number: NCT06433674

Study to Assess the Effect of Zinc in Atorvastatin Treated Hyperlipidemic Patients

Phase 2

Conditions: Hyperlipidemias

Interventions: Drug: Zinc sulfate
Drug: Placebo

First Posted Date: 2022-05-27

Last Posted Date: 2022-05-27

Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Target Recruit Count: 92

Registration Number: NCT05395143

Locations: 🇧🇩
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial

Phase 4

Completed

Conditions: Preterm Infant
Effect of Drugs
Zinc Deficiency Disease

Interventions: Drug: Zinc Sulfate

First Posted Date: 2022-04-05

Last Posted Date: 2023-02-08

Lead Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital

Target Recruit Count: 195

Registration Number: NCT05311540

Locations: 🇹🇷
Izmir Democracy University Faculty of Medicine, Izmir, Turkey

Effect of Oral Zinc Sulfate on Jaundice in Neonates Admitted to Neonatal Intensive Care Unit

Not Applicable

Completed

Conditions: Serum Bilirubin

Interventions: Drug: Zinc sulfate
Other: Placebo
Other: Phototherapy

First Posted Date: 2021-12-17

Last Posted Date: 2022-08-30

Lead Sponsor: Makassed General Hospital

Target Recruit Count: 60

Registration Number: NCT05161611

Locations: 🇱🇧
Makassed General Hospital, Beirut, Lebanon

Hydroxychloroquine and Zinc With Either Azithromycin or Doxycycline for Treatment of COVID-19 in Outpatient Setting

Phase 4

Completed

Conditions: COVID-19

Interventions: Drug: Hydroxychloroquine
Drug: Zinc Sulfate
Drug: Azithromycin
Drug: Doxycycline

First Posted Date: 2020-05-01

Last Posted Date: 2020-12-09

Lead Sponsor: St. Francis Hospital, New York

Target Recruit Count: 18

Registration Number: NCT04370782

Locations: 🇺🇸
St Francis Hospital, Roslyn, New York, United States

Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia

Phase 2

Completed

Conditions: Vaso-occlusive Crisis
Sickle Cell Disease
Sickle Cell Anemia in Children

Interventions: Drug: Omega 3
Drug: Statins (Cardiovascular Agents)
Drug: Vit D
Drug: Zinc sulfate
Drug: Hydroxy Urea
Drug: Folic Acid Supplementation
Drug: Morphine Sulfate
Procedure: blood transfusion session

First Posted Date: 2020-03-10

Last Posted Date: 2021-01-27

Lead Sponsor: Beni-Suef University

Target Recruit Count: 350

Registration Number: NCT04301336

Locations: 🇪🇬
Faculty of Pharmacy, Beni-Suef university, Banī Suwayf, Egypt
🇪🇬
Health insurance hospital, Banī Suwayf, Egypt
🇪🇬
Faculty of medicine, Beni-suef univeristy - Beni-Seuf university hospital, Banī Suwayf, Egypt

and more 1 locations

Drug Development Updates

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