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Sunvozertinib

Generic Name
Sunvozertinib
Indication

用于既往经含铂化疗治疗时或治疗后出现疾病进展,或不耐受含铂化疗,并且经检测确认存在表皮生长因子受体(EGFR)20号外显子插入突变的局部晚期或转移性非小细胞肺癌(NSCLC)的成人患者。

Assessing an Oral EGFR Inhibitor, DZD9008 in Patients With Advanced Non-small Cell Lung Cancer(NSCLC) With EGFR Mutations (WU-KONG15)

Not Applicable
Recruiting
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2022-09-29
Last Posted Date
2024-05-29
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
180
Registration Number
NCT05559645
Locations
🇨🇳

Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Beijing, Beijing, China

Assessing the Safety, Tolerability and Pharmacokinetics(PK) of DZD9008 and the Effect of Low-fat Meal on PK of DZD9008 in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Placebo
First Posted Date
2021-06-01
Last Posted Date
2022-06-02
Lead Sponsor
Dizal Pharmaceuticals
Target Recruit Count
78
Registration Number
NCT04909242
Locations
🇺🇸

PRA Health Sciences, Lenexa, Kansas, United States

Assessing an Oral Bruton Tyrosine Kinase Inhibitor, DZD9008 in Patients Who Have Non-Hodgkin B-cell Lymphoma (WU-KONG3)

Phase 1
Withdrawn
Conditions
Non-Hodgkin's B-cell Lymphoma
Interventions
First Posted Date
2019-11-01
Last Posted Date
2025-02-25
Lead Sponsor
Dizal Pharmaceuticals
Target Recruit Count
120
Registration Number
NCT04148742
Locations
🇨🇳

Jiangsu Province Hospital - Haematology, Nanjing, China

🇨🇳

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Nanjing, China

Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer with EGFR or HER2 Mutation (WU-KONG1)

Phase 1
Active, not recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2019-06-04
Last Posted Date
2025-02-28
Lead Sponsor
Dizal Pharmaceuticals
Target Recruit Count
315
Registration Number
NCT03974022
Locations
🇮🇹

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori - IRST IRCCS, Meldola, Italy

🇯🇵

Okayama University Hospital, Okayama-Shi, Japan

🇪🇸

Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

and more 121 locations
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