MedPath

Metoprolol Succinate/Empagliflozin/Spironolactone

Generic Name
Metoprolol Succinate/Empagliflozin/Spironolactone

Polypill for Prevention of Cardiomyopathy

Phase 1
Recruiting
Conditions
Type 2 Diabetes
High Blood Pressure
Interventions
First Posted Date
2023-11-22
Last Posted Date
2024-03-12
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
60
Registration Number
NCT06143566
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

Polypill in Acute Coronary Syndrome

Phase 2
Recruiting
Conditions
Lipid Disorder
Coronary Artery Disease
Acute Coronary Syndrome
Interventions
Drug: Usual Care (individual medications prescribed by primary cardiologist)
First Posted Date
2022-08-25
Last Posted Date
2025-04-16
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
120
Registration Number
NCT05514938
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

Polypill Strategy for Heart Failure With Reduced Ejection Fraction

Early Phase 1
Recruiting
Conditions
Heart Failure
Interventions
Drug: Control Rx
First Posted Date
2020-11-17
Last Posted Date
2025-01-07
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
175
Registration Number
NCT04633005
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

A Polypill for Secondary Prevention of Ischemic Heart Disease

Phase 3
Conditions
Non-ST Elevation Myocardial Infarction
Acute Myocardial Infarction
ST Elevation Myocardial Infarction
Interventions
First Posted Date
2018-05-30
Last Posted Date
2020-10-14
Lead Sponsor
Isfahan University of Medical Sciences
Target Recruit Count
1200
Registration Number
NCT03541109
Locations
🇮🇷

Chamran cardiology hospital, Isfahan, Iran, Islamic Republic of

🇮🇷

Cardiovascular Research Institute, Isfahan, Iran, Islamic Republic of

Prevention of Cardiovascular Disease With Polypill Among Pars Cohort Participants

Phase 3
Conditions
Cardiovascular Diseases
Interventions
First Posted Date
2018-03-09
Last Posted Date
2021-02-10
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
4415
Registration Number
NCT03459560
Locations
🇮🇷

Pars Cohort Center, Shiraz, Fars, Iran, Islamic Republic of

Prevention of Cardiovascular Disease in Middle-aged and Elderly Iranians Using a Single PolyPill

Phase 3
Completed
Conditions
Cardiovascular Diseases
Interventions
Other: Minimal care
First Posted Date
2011-01-07
Last Posted Date
2019-01-22
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
8410
Registration Number
NCT01271985
Locations
🇮🇷

Golestan Cohort Study Center, Gonbad, Golestan, Iran, Islamic Republic of

Prevention of Cardiovascular Disease Using a Single PolyPill in an Urban Population - Focus on Liver-Related Variables.

Phase 3
Completed
Conditions
Cardiovascular Diseases
Interventions
First Posted Date
2010-11-22
Last Posted Date
2019-02-15
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
2400
Registration Number
NCT01245608
Locations
🇮🇷

Golestan Cohort Center, Gonbad, Golestan, Iran, Islamic Republic of

UMPIRE - Use of a Multidrug Pill In Reducing Cardiovascular Events

Phase 3
Completed
Conditions
Cardiovascular Diseases
Interventions
Drug: Usual cardiovascular medications
First Posted Date
2010-01-27
Last Posted Date
2012-11-27
Lead Sponsor
Imperial College London
Target Recruit Count
2004
Registration Number
NCT01057537
Locations
🇮🇳

George Institute for International Health - India, Hyderabad, India

🇮🇳

Public Health Foundation of India, New Dehli, India

🇮🇪

Royal College of Surgeons in Ireland Research Institute, Dublin, Ireland

and more 4 locations

Phase II Study of Heart Polypill Safety and Efficacy in Primary Prevention of Cardiovascular Disease

Phase 2
Completed
Conditions
Cardiovascular Disease
Hypertension
Hyperlipidemia
Heart Disease
Interventions
Drug: Placebo drug
First Posted Date
2008-01-29
Last Posted Date
2009-10-02
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
475
Registration Number
NCT00603590
Locations
🇮🇷

Kalaleh Heart Study Center, Kalaleh, Golestan, Iran, Islamic Republic of

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