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Midomafetamine

Generic Name
Midomafetamine
Drug Type
Small Molecule
Chemical Formula
C11H15NO2
CAS Number
42542-10-9
Unique Ingredient Identifier
KE1SEN21RM
Background

An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.

Indication

Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.

Role of Serotonin in Acute and Subacute MDMA Effects

Not Applicable
Completed
Conditions
MDMA Mechanism of Action
Interventions
First Posted Date
2009-02-06
Last Posted Date
2013-05-31
Lead Sponsor
California Pacific Medical Center Research Institute
Target Recruit Count
13
Registration Number
NCT00838305
Locations
🇺🇸

CPMC Research Institute, St.Luke's Hospital, San Francisco, California, United States

Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder

Phase 2
Completed
Conditions
Posttraumatic Stress Disorder
Interventions
Drug: 3,4-methyelendioxymethamphetamine (25 mg)
Behavioral: Therapy
First Posted Date
2006-07-19
Last Posted Date
2024-07-15
Lead Sponsor
Lykos Therapeutics
Target Recruit Count
14
Registration Number
NCT00353938
Locations
🇨🇭

Offices of Peter Oehen MD, Biberist, Solothurn, Switzerland

MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer

First Posted Date
2005-11-11
Last Posted Date
2017-11-14
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
2
Registration Number
NCT00252174
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

Phase 2
Completed
Conditions
Posttraumatic Stress Disorder
Interventions
First Posted Date
2004-08-25
Last Posted Date
2024-11-05
Lead Sponsor
Lykos Therapeutics
Target Recruit Count
23
Registration Number
NCT00090064
Locations
🇺🇸

Offices of Michael Mithoefer MD, Mount Pleasant, South Carolina, United States

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