Lactose

Generic Name: Lactose

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₂₂O_₁₁

CAS Number: 63-42-3

Unique Ingredient Identifier: 3SY5LH9PMK

Background: A disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.

Indication: Not Available

Associated Conditions: Asthma, Chronic Obstructive Pulmonary Disease (COPD), Hypothyroidism, Opioid Dependence, Thyroid Cancer

Associated Therapies: Maintenance treatment, opioids, Opioid Detoxification

Clinical Trials

Amantadine for COVID-19

Phase 3

Conditions: Covid19

Interventions: Drug: Lactose monohydrate
Drug: Amantadine

First Posted Date: 2021-05-20

Last Posted Date: 2021-10-06

Lead Sponsor: Copenhagen University Hospital, Hvidovre

Target Recruit Count: 226

Registration Number: NCT04894617

Locations: 🇩🇰
Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark

Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery

Phase 2

Recruiting

Conditions: Pain, Postoperative
Narcotic Use

Interventions: Drug: Melatonin 10 MG
Drug: Lactose pill

First Posted Date: 2021-03-10

Last Posted Date: 2024-06-12

Lead Sponsor: Montefiore Medical Center

Target Recruit Count: 60

Registration Number: NCT04791943

Locations: 🇺🇸
Montefiore Medical Center Department of Dentistry, Bronx, New York, United States

A Comparison of Two Different Single Doses of Prednisolone on Endodontic Inter-appointment Pain

Phase 2

Conditions: Endodontics
Pain

Interventions: Drug: Prednisolone
Drug: lactose in capsules gelatin

First Posted Date: 2020-07-22

Last Posted Date: 2020-07-22

Lead Sponsor: King Saud University

Target Recruit Count: 72

Registration Number: NCT04481971

Human Cerebral Blood Flow Regulation

Early Phase 1

Recruiting

Conditions: Cerebral Arterial Diseases

Interventions: Drug: Indomethacin 25 MG/50 MG
Drug: Placebo - Lactose
Drug: Ganirelix Acetate
Drug: Testosterone Transdermal Product
Drug: Estradiol Topical
Drug: Antacid

First Posted Date: 2020-02-11

Last Posted Date: 2025-04-17

Lead Sponsor: University of Wisconsin, Madison

Target Recruit Count: 111

Registration Number: NCT04265053

Locations: 🇺🇸
University of Wisconsin, Madison, Madison, Wisconsin, United States

Feasibility of a Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel

Phase 3

Completed

Conditions: Lung Cancer
Ovarian Cancer
Breast Cancer
Oesophageal Cancer
Head Cancer Neck
Cervical Cancer
Endometrial Cancer

Interventions: Drug: Cetirizine
Drug: Diphenhydramine
Drug: Lactose pill
Drug: Sodium chloride 0.9%

First Posted Date: 2020-01-22

Last Posted Date: 2020-10-12

Lead Sponsor: Ciusss de L'Est de l'Île de Montréal

Target Recruit Count: 27

Registration Number: NCT04237090

Locations: 🇨🇦
CIUSSS de l'Est-de-l'île-de-Montréal, Montréal, Quebec, Canada

Investigation of Nicotine Seeking Behavior in Current Smokers

Phase 1

Completed

Conditions: Cigarette Smoking

Interventions: Drug: Lactose Monohydrate Powder
Drug: Yohimbine Hydrochloride
Drug: Hydrocortisone

First Posted Date: 2018-09-13

Last Posted Date: 2018-09-13

Lead Sponsor: Wayne State University

Target Recruit Count: 21

Registration Number: NCT03670212

Locations: 🇺🇸
Wayne State University, Detroit, Michigan, United States

PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2

Phase 3

Completed

Conditions: Elbow Fracture
Elbow Injury
Elbow Dislocation

Interventions: Drug: Lactose Placebo
Drug: Ketotifen Fumarate 2mg
Drug: Ketotifen Fumarate 5mg

First Posted Date: 2018-07-10

Last Posted Date: 2025-03-20

Lead Sponsor: University of Calgary

Target Recruit Count: 395

Registration Number: NCT03582176

Locations: 🇨🇦
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
🇺🇸
University of Maryland Medical Centre, Baltimore, Maryland, United States
🇨🇦
St. Paul's Hospital, Vancouver, British Columbia, Canada

and more 12 locations

Preventing Recurrent Urinary Tract Infections With α-D-mannose

Phase 4

Terminated

Conditions: Urinary Tract Infections

Interventions: Drug: Mannose
Drug: Lactose

First Posted Date: 2018-04-13

Last Posted Date: 2020-09-02

Lead Sponsor: Kantonsspital Aarau

Target Recruit Count: 15

Registration Number: NCT03497598

Locations: 🇨🇭
Kantonsspital Aarau, Aarau, Switzerland

Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients with Cocaine Addiction

Phase 2

Terminated

Conditions: Cocaine Addiction

Interventions: Drug: Lactose powder
Drug: N-acetylcysteine

First Posted Date: 2018-02-06

Last Posted Date: 2025-02-07

Lead Sponsor: Salvatore Campanella

Target Recruit Count: 33

Registration Number: NCT03423667

Locations: 🇧🇪
CHU Brugmann, Brussels, Belgium

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

Phase 2

Recruiting

Conditions: Diabetic Macular Edema
Diabetic Retinopathy

Interventions: Drug: DR lactose pill
Drug: DR vitrectomy lactose pill
Drug: DME plus ranibizumab levosulpiride
Drug: DR levosulpiride
Drug: DME levosulpiride
Drug: DR vitrectomy levosulpiride
Drug: DME lactose pill
Drug: DME plus ranibizumab lactose pill

First Posted Date: 2017-05-22

Last Posted Date: 2024-12-06

Lead Sponsor: Carmen Clapp

Target Recruit Count: 120

Registration Number: NCT03161652

Locations: 🇲🇽
Instituto de la Retina del Bajio SC (INDEREB), Querétaro City, Queretaro, Mexico
🇲🇽
Instituto Mexicano de Oftalmologia (IMO), Queretaro, Mexico

Drug Development Updates

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