Cetirizine
- Generic Name
- Cetirizine
- Brand Names
- Aller-tec, Aller-tec D, Quzyttir, Reactine, Wal Zyr 24 Hour Allergy, Wal Zyr D, Wal-zyr, Zerviate, Zyrtec, Zyrtec-D
- Drug Type
- Small Molecule
- Chemical Formula
- C21H25ClN2O3
- CAS Number
- 83881-51-0
- Unique Ingredient Identifier
- YO7261ME24
- Background
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
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- Indication
Seasonal Allergic Rhinitis: Indicated for the relief of symptoms associated with seasonal allergic rhinitis caused by allergens such as ragweed, grass and tree pollens in adults and children 2 years of age and above. Symptoms treated effectively include sneezing, rhinorrhea, nasal pruritus, ocular pruritus, tearing, and redness of the eyes .
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- Associated Conditions
- Allergy to Tree Pollen, Chronic Idiopathic Urticaria, Flu caused by Influenza, Perennial Allergic Rhinitis (PAR), Respiratory Allergy, Seasonal Allergic Rhinitis
- Associated Therapies
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Organ Protective Effect of Cetirizine In Patients With Severe Burns
- First Posted Date
- 2023-11-13
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- Ruijin Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT06126991
- Locations
- 🇨🇳
Department of Burn, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
The Effect of Switching the H1-antagonist Clemastine to Cetirizine in Premedication Regimens During Paclitaxel Treatment
- First Posted Date
- 2023-09-15
- Last Posted Date
- 2024-02-20
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 395
- Registration Number
- NCT06039137
- Locations
- 🇳🇱
Erasmus University Medical Center, Rotterdam, Zuid-Holland, Netherlands
Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial
- Conditions
- Interventions
- First Posted Date
- 2023-07-14
- Last Posted Date
- 2024-08-21
- Lead Sponsor
- Emory University
- Target Recruit Count
- 5
- Registration Number
- NCT05946551
- Locations
- 🇺🇸
Grady Health System, Atlanta, Georgia, United States
🇺🇸Emory Hospital, Atlanta, Georgia, United States
🇺🇸Emory University Hospital Midtown, Atlanta, Georgia, United States
The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers
- Conditions
- Interventions
- First Posted Date
- 2021-10-27
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 16
- Registration Number
- NCT05095311
- Locations
- 🇺🇸
1025 E Seventh St, Bloomington, Indiana, United States
Topical Cetirizine 1% vs Minoxidil 5% Gel in Treatment of Androgenetic Alopecia
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2020-03-04
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT04293822
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Feasibility of a Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel
- First Posted Date
- 2020-01-22
- Last Posted Date
- 2020-10-12
- Lead Sponsor
- Ciusss de L'Est de l'Île de Montréal
- Target Recruit Count
- 27
- Registration Number
- NCT04237090
- Locations
- 🇨🇦
CIUSSS de l'Est-de-l'île-de-Montréal, Montréal, Quebec, Canada
Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia
- Conditions
- Interventions
- First Posted Date
- 2017-06-20
- Last Posted Date
- 2020-06-16
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 13
- Registration Number
- NCT03192488
- Locations
- 🇺🇸
Indiana University, Bloomington, Indiana, United States
Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2017-05-25
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 20
- Registration Number
- NCT03167216
- Locations
- 🇺🇸
Northwestern Medical Faculty Foundation, Chicago, Illinois, United States
Randomized, Double Blind, Parallel Group, Placebo Controlled, Multi-Center Study of the Efficacy and Safety of Cetirizine HCl Syrup vs. Loratadine Syrup vs. Placebo in Treatment of Children With Seasonal Allergic Rhinitis (SAR)
- Conditions
- Interventions
- First Posted Date
- 2016-10-13
- Last Posted Date
- 2017-04-20
- Target Recruit Count
- 683
- Registration Number
- NCT02932774
Neuromyelitis Optica (NMO) & Cetirizine
- First Posted Date
- 2016-08-12
- Last Posted Date
- 2023-06-07
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 16
- Registration Number
- NCT02865018
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Drug Development Updates
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