Melatonin
- Generic Name
- Melatonin
- Brand Names
- Circadin, Slenyto, Melatonin Neurim
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2O2
- CAS Number
- 73-31-4
- Unique Ingredient Identifier
- JL5DK93RCL
- Background
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence ...
- Indication
Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for ...
- Associated Conditions
- Insomnia
- Associated Therapies
- -
Melatonin for Pulmonary Hypertension in Full Term Neonates
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 40
- Registration Number
- NCT06685679
- Locations
- 🇪🇬
Ain shams university, Cairo, Egypt
ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments
- Conditions
- Interventions
- First Posted Date
- 2024-05-24
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Duke University
- Target Recruit Count
- 50
- Registration Number
- NCT06429059
- Locations
- 🇺🇸
Temple University, Philadelphia, Pennsylvania, United States
🇺🇸Duke University Medical Center, Durham, North Carolina, United States
Clinical Trial for the Evaluation of Melatonin in the Treatment of Pressure Ulcers
- First Posted Date
- 2024-05-20
- Last Posted Date
- 2024-05-20
- Lead Sponsor
- Fundacion Rioja Salud
- Target Recruit Count
- 50
- Registration Number
- NCT06421454
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
- Conditions
- Interventions
- First Posted Date
- 2024-05-08
- Last Posted Date
- 2024-08-01
- Lead Sponsor
- Duke University
- Target Recruit Count
- 600
- Registration Number
- NCT06404112
- Locations
- 🇺🇸
All sites listed under NCT06404086, Durham, North Carolina, United States
of Myo-inositol, Melatonin and Co-enzyme q10 on Ovarian Reserve
- Conditions
- Interventions
- First Posted Date
- 2024-05-08
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 200
- Registration Number
- NCT06405204
- Locations
- 🇪🇬
Beni-suef university Hospital, Banī Suwayf, Egypt
RECOVER-SLEEP: Platform Protocol
- First Posted Date
- 2024-05-08
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1074
- Registration Number
- NCT06404086
- Locations
- 🇺🇸
University of Florida College of Medicine Jacksonville, Jacksonville, Florida, United States
🇺🇸Brigham and Womens Hospital, Boston, Massachusetts, United States
🇺🇸Boston Medical Center, Boston, Massachusetts, United States
Melatonin in Obese Patients in Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2024-04-09
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT06355687
Improving Sleep of Children With Neurodevelopmental Disorders: Pulsed Current Stimulation Versus Melatonin
- Conditions
- Interventions
- First Posted Date
- 2024-02-01
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- KK Women's and Children's Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT06236191
- Locations
- 🇸🇬
KKWCH, Singapore, Singapore
Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
- First Posted Date
- 2024-01-26
- Last Posted Date
- 2024-08-28
- Lead Sponsor
- Leslie Swanson
- Target Recruit Count
- 50
- Registration Number
- NCT06226025
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
Comparing the Effect of Melatonin, Diazepam, and Placebo on Decreasing the Level of Anxiety Preoperatively
- Conditions
- Interventions
- First Posted Date
- 2023-10-26
- Last Posted Date
- 2023-10-27
- Lead Sponsor
- University of Jordan
- Target Recruit Count
- 87
- Registration Number
- NCT06103188
- Locations
- 🇯🇴
Jordan University Hospital, Amman, Jordan
Drug Development Updates
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