Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.

Used to treat potentially life threatening fungal infections.

• Coccidioidomycosis
• Fungal Infections
• Histoplasmosis
• Invasive Aspergillosis
• Invasive Fungal Infections
• Leishmaniasis
• Meningitis, Cryptococcal
• Meningitis, Fungal
• Mucocutaneous Leishmaniasis
• Mycotic endophthalmitis
• Penicillium marneffei infection
• Visceral Leishmaniasis
• Candidal cystitis
• Disseminated Cryptococcosis
• Fungal osteoarticular infections
• Ocular aspergillosis
• Refractory aspergillosis
• Severe Coccidioidomycosis
• Severe Cryptococcosis
• Severe Fungal infection caused by Basidiobolus spp.
• Severe Fungal infection caused by Conidiobolus spp.
• Severe Fungal infection caused by sporotrichosis spp.
• Severe Histoplasmosis
• Severe Mucocutaneous leishmaniasis
• Severe North American blastomycosis
• Severe Systemic candidiasis