Penciclovir
- Generic Name
- Penciclovir
- Brand Names
- Denavir
- Drug Type
- Small Molecule
- Chemical Formula
- C10H15N5O3
- CAS Number
- 39809-25-1
- Unique Ingredient Identifier
- 359HUE8FJC
- Background
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
- Indication
Used to treat recurrent cold sores on the lips and face from various herpesvirus invections.
- Associated Conditions
- Cold Sore
- Associated Therapies
- -
Dr Schiff on PFS and OS Data With Temozolomide Plus Radiation in Grade II Glioma
Temozolomide combined with radiation significantly improved overall survival in grade II glioma patients, with a hazard ratio of 0.54. Similar benefits were observed in patients with 1p/19q codeletions or astrocytoma. Temozolomide is considered a reasonable alternative to procarbazine, lomustine, and vincristine (PCV) until definitive results from a 2006-2007 randomized trial are available.
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